Multifunctional bioprotein-based aerogel material as well as preparation method and application thereof

A biological protein and aerogel technology, applied in the field of materials, can solve the problems of single function, poor mechanical properties of biological protein aerogels, lack of functional properties such as medicinal properties, etc., and achieve high filtration efficiency, excellent biocompatibility and Effects of degradability, high catalytic and dissolution properties

Active Publication Date: 2022-07-12
ANHUI UNIVERSITY OF TECHNOLOGY AND SCIENCE
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, traditional bioprotein aerogels generally have poor mechanical properties, relatively single functions, and lack of functional properties such as medicinal properties.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Multifunctional bioprotein-based aerogel material as well as preparation method and application thereof
  • Multifunctional bioprotein-based aerogel material as well as preparation method and application thereof
  • Multifunctional bioprotein-based aerogel material as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A preparation method of a multifunctional biological protein-based aerogel material, comprising the following steps:

[0041] 1) prepare a deep eutectic solvent, and the raw material composition of the partial preparation solvent is as follows figure 1 shown. In this example, cysteine ​​and lactic acid are used as examples, and the specific method for preparing the deep eutectic solvent is as follows: measure 5g cysteine ​​and 40ml of lactic acid aqueous solution with a mass concentration of 80% and add them into a conical flask; put them into a magnetic stirrer , dissolve at 110°C for two hours, and set aside for use; immerse the washed and dried down in a synthetic deep eutectic solvent, control the bath ratio to 40:1, dissolve and peel down the down fibers at 100°C, and control the peeling time at 4 Within hours, a translucent viscous red liquid was formed.

[0042] 2) At room temperature of 25°C, dialyze the solution obtained in step 1) with a dialysis bag of 8KD-...

Embodiment 2

[0046]The application of a multifunctional biological protein-based aerogel material, which is used to prepare a hydrophobic material. The hydrophobic multifunctional aerogel material is prepared by a vapor deposition method. The specific method is as follows: taking 3 ml of methyltrimethoxysilane and 1.5 ml of The water was put into two open vials, and the two vials were placed in a closed container together with the aerogel prepared in Example 1 (cylindrical, with a height of 1.2 cm and a bottom diameter of 5 cm). The silanized aerogel material was placed in a vacuum oven at 60°C for 12 hours to remove excess methyltrimethoxysilane and complete the hydrophobic modification.

[0047] Taking the same size aerogel material without hydrophobic modification, as the material before modification and the above modified material, the following tests were carried out:

[0048] The same method was used to drip water on the surface of the aerogel before and after modification. Before th...

Embodiment 3

[0050] An application of a multifunctional biological protein-based aerogel material for drug loading, the drug-loaded aerogel material is prepared by a eutectic method, and the specific method is as follows:

[0051] The commercially available Coptis chinensis extract was dissolved in the feather protein fibril dispersion after dialysis in Example 1 step 2), and the mass ratio of the Coptis chinensis extract and the dialysis post-dialysis feather protein fibril dispersion was set to 1:20, and the prepared total was 1:20. The melt system was ultrasonically treated in a Scientz-CHF-5B ultrasonic bath at a frequency of 40 kHz under the condition of 400W for 2 hours to increase the degree of fusion between the two. During the ultrasonic treatment, an ice bath environment was maintained to avoid the oxidative decomposition of berberine. After that, the dispersion liquid was poured into a polytetrafluoroethylene mold, and pre-frozen at -60 °C for 15 hours, and then freeze-dried in a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
densityaaaaaaaaaa
contact angleaaaaaaaaaa
porosityaaaaaaaaaa
Login to view more

Abstract

According to the multifunctional bioprotein-based aerogel material as well as the preparation method and the application thereof provided by the invention, a biomass fiber fibril mixed component with a micro-nano size is extracted by adopting a deep eutectic solvent stripping technology, and an aerogel core material prepared by adopting a freeze drying process forms a fibril interpenetrating stable three-dimensional network structure; the mechanical property of the core material is improved, and the core material has excellent biocompatibility and degradability. Moreover, based on co-melting and vapor deposition schemes, the aerogel core material with the drug-loading function and the hydrophobic material are prepared, functionalization of the material is achieved, and the aerogel material with the drug-loading function can also be used for manufacturing detachable masks and plays a role in disease prevention. The drug-loaded multifunctional bioprotein-based aerogel core material provided by the invention has excellent biocompatibility and degradability, the raw materials are wide in source, and the core material can be self-degraded after being discarded without subsequent treatment cost.

Description

technical field [0001] The invention belongs to the field of materials, and in particular relates to a multifunctional biological protein-based aerogel material and a preparation method and application thereof. Background technique [0002] Aerogel core material has a hierarchical porous structure, which can achieve physical barrier and storage of polluting particles, improve filtration efficiency, and has high application value in the field of protective products. [0003] Extracting protein from biological resources such as feathers and low-value silk has the advantages of low cost and abundant resources. Therefore, the development of biological protein-based aerogel core materials meets the requirements of the "two-carbon" target. [0004] However, traditional biological protein aerogels generally have poor mechanical properties, relatively single function, and lack of functional properties such as medicinal properties. SUMMARY OF THE INVENTION [0005] Based on the an...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C08J9/28C08L89/00A41D13/11
CPCC08J9/28A41D13/1192C08J2389/00C08J2201/0484A41D2400/32A41D2400/70
Inventor 王宗乾杨海伟杨其亮卜凡李长龙刘志郑嫚嫚黄江胜
Owner ANHUI UNIVERSITY OF TECHNOLOGY AND SCIENCE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap