Method for producing bacteria powder containing lovastatin by liquid submerged fermentation

A technology of liquid submerged fermentation and lovastatin, applied in microorganism-based methods, biochemical equipment and methods, fermentation and other directions, can solve the problems of large blood lipid lowering effect, small market share, easy product pollution, etc., and achieve good results , The effect of low labor intensity and less impurities

Inactive Publication Date: 2006-02-15
HUBEI CHEM FIBER GROUP
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  • Abstract
  • Description
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Problems solved by technology

But generally speaking, the market share of functional red yeast rice products is not large. The lovastatin produced by Monascus fungus has a great effect on lowering blood lipids and has no side effects. However, the functional red yeast rice produced in my country still uses Qupan Or the ancient method of making koji by ventilating, the labor intensity is high, the product is easy to be polluted, and the product contains low lovastatin

Method used

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Embodiment Construction

[0043] The specific implementation method of the production of the Monascus thallus powder provided by the invention is divided into five parts:

[0044] 1. Monascus slant pure culture.

[0045] 2. Cultivation of primary and secondary shake flask seeds.

[0046] 3. Cultivation of monascus seed tanks.

[0047] 4. Monascus fermentation cultivation;

[0048] 5. Refining, homogenizing, and spray-drying to form powder—the finished product—monascus powder containing 1.2% lovastatin.

[0049] Below we describe the present invention in detail by specific implementation method:

[0050] 1. Cultivation of slant purebred:

[0051] ① Preparation of slant medium:

[0052] Mix 100 ml of wort juice and 3 grams of agar, adjust the pH value to 3.5, heat to make the agar fully dissolve, then divide into test tubes, stuff them with cotton plugs, sterilize with 1 kg / 30 minutes, and place them on an inclined plane for later use;

[0053] ②Preparation of slanted purebred:

[0054] The above ...

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Abstract

The invention can be used to get farlutating thallus powder by deep submerged fermentation in liquid. Whicn can be used to make all kinds of food or drug for depress blood fat. The whole manufactory process of monascus thalli powder follows five steps. 1, pure bred on bevel. 2, rocking seed in two level. 3, culture in seed tank. 4, fermentation and culture in fermenter tank..5, get monascus thalli powder containing 1.2% farlutating after abrading, isotroping and atomized drying the monascus thalli. The craft is easy and parameter can be controlled. The whole production is airproof so it is different to be polluted. The outcome is pure and its quality is good. Besides, the labour intensity is low.

Description

Technical field: [0001] The invention relates to a method for preparing bacterial strain powder, in particular to a method for producing bacterial powder containing 1.2% lovastatin by a liquid submerged fermentation method. Background technique: [0002] Monascus is the main strain used to produce red yeast rice wine and red yeast pigment. It has a history of thousands of years in China. The application of food coloring, food preservation and medical treatment has been loaded. In 1979, after Professor Akira Endo of Japan isolated the cholesterol synthesis inhibitor from Monascus ruber, the function and application of Monascus have attracted widespread attention at home and abroad, and have been comprehensively and in-depth researched. Many food companies in Japan have invested a lot of manpower and material resources The red yeast rice health food has been developed and marketed, and the products that can lower blood fat are very popular, but for the inventor of red yeast r...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12P17/06C12N1/14C12R1/66
Inventor 王卫民曹云龙
Owner HUBEI CHEM FIBER GROUP
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