Artificial skin and its prepn and use

Abstract

The artificial skin consists of skeleton material and polysaccharide in the weight ratio of 0.1-30:1 as well as some supplementary material. The artificial skin in two kinds, with pores and without pores, may be used in the treatment of burns, wound, frostbite, ulcer and beauty treatment operation. Test shows that using the artificial skin to cover wound area can promote heat of the wound area, eliminate diffusate from the wound, prevent and treat bacteria infection, and reduce the irritation to skin. In addition, it has excellent flexibility and strength and may be uncovered from wound without pain produced.

Description

technical field [0001] The invention relates to the field of medicine, and provides an artificial skin for covering surgical wounds and grade 2 and 3 wounds. Background technique [0002] At present, there are many dressings for treating skin wounds, which are generally divided into three categories: ordinary dressings, biological dressings and synthetic dressings. People generally refer to the film-like dressing as "artificial skin". A better artificial skin is a sheet or film made of polymer compounds or biopolymers. However, coverings composed only of polymer compounds, such as those made of polyurethane, or polyurethane and ethers, although they have good physical properties, are very strong, water-permeable, Breathable, but only completes the task of protecting the wound surface, and does not have the property of stimulating the growth and recovery of the wound surface; on the other hand, the covering composed only of biopolymers, such as collagen or gelatin and chito...

AI Technical Summary

Problems solved by technology

However, coverings composed only of polymer compounds, such as those made of polyurethane, or polyurethane and ethers, although they have good physical properties, are very strong, water-permeable, Breathable, but only completes the task of protecting the wound surface, and does not have the property of stimulating the growth and recovery of the wound surface; on the other hand, the covering composed only of biopolymers, such as collagen or gelatin and chitosan A mixture of collagen, chitosan, and glycosaminoglycan polymers can stimulate wound growth well, but has poor physical properties: brittle when dry and easily broken when wet , and is quickly decomposed under the action of wound exudate enzymes, unable to complete the protection task

In addition CN1117708 has introduced a kind of absorbent wound dressing, mainly reaches the purpose of absorbing wound exudate by adding hydrophilic polymer, but it has only reached protection wound from being infected again, can not promote wound healing; CN1162268 has introduced a A wound dressing with improved water vapor permeability and low damage; CN1095916 introduces a wound dressing with a polymer as the bottom layer, which is considered to be a novel wound dressing with excellent absorbency and prevent leakage, which contains continuous and discontinuous hydrocolloids

But they all have such defect, promptly have irritation, make skin have micro-burning sensation; Strength is weaker, easy to break easily when used; Infect easily when there is oozing wound and use; Preparation process is complicated