Implanted slow-releasing antiseptic preparation and its preparing method

An antibacterial and sustained-release technology, applied in the field of medicine, can solve the problems of repairing between occluded tissues, inconvenient use, application limitations, etc., and achieve the effects of reducing toxic side effects, reducing usage, and reducing occlusion.
CN1351868AInactive Publication Date: 2002-06-05SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
Publication Date
2002-06-05
Estimated Expiration
Not applicable · inactive patent
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Abstract

The present invention relates to the field of medical technology. By using carboxymerhyl chitosan as slow-releasing assistant and antiseptic as carrier and through emulsification and crosslinking process, a kind of degradable slow-releasing microball is prepared capable of being implanted in operation incision to prevnet post-operational local infection. The slow-releasing preparation of the present invention has the features of degradability and small volume, and avoids the shield to biological repair in oganism.
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Description

technical field

[0001] The invention relates to the technical field of medicine, and relates to a degradable implanted slow-release dosage form of antibacterial drugs and a preparation method thereof. Background technique

[0002] Usually all will use antibacterial medicine for a certain period of time after surgical operation to prevent the infection of patient's surgical incision, especially traumatic operation, implant implantation operation, open wound operation etc. The traditional route of administration of antibacterial drugs is intravenous, oral, intramuscular injection and so on. These systemic medication methods have obvious deficiencies: 1. There are systemic toxicity and side effects; 2. Insufficient local drug concentration; 3. Inconvenient use, etc. Therefore, local implant dosage forms of antibacterial drugs are increasingly concerned by clinicians. At present, implanted slow-release formulations of different antibacterial drugs have been used in clinical pr...

Claims

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