Cetirizing hydrochloride cataplasm preparation

Abstract

The present invention relates to medicine technology and is cataplasm as one new form of Cetirizine hydrochloride. There are available oral forms of Cetirizine hydrochloride, such as tablet, capsule, solution preparation, etc. The present invention prepares the cataplasm with Cetirizine hydrochloride as main medicine component and different supplementary material, and the cataplasm is administrated via skin. The present invention can avoid stimulation to gastrointestinal tract of the medicine, reduce medicine concentration in blood, reduce central nerve suppressing effect, raise the medicine concentration in local affected part, decrease the administration times and raise patient's compatibility.

Description

Technical field:

[0001] The invention relates to the technical field of medicine, and relates to a new dosage form of the antihistamine cetirizine hydrochloride—a cataplasm. Background technique:

[0002] Cetirizine hydrochloride is a second-generation antihistamine, which has a good therapeutic effect on allergic diseases of the skin, respiratory system and eyes, such as skin urticaria, allergic asthma, allergic rhinitis and allergic conjunctivitis. At present, the pharmaceutical dosage forms of this medicine include conventional dosage forms such as tablets, capsules, and solutions, and the route of administration is all oral. Compared with other antihistamines, although the central nervous system activity of cetirizine hydrochloride is lower, the drug still has adverse reactions such as drowsiness, dizziness, and headache when taken orally. Invention content:

[0003] The invention provides a transdermal drug delivery preparation of cetirizine hydrochloride - cataplasm...