Tenuifolia volatile oil, and formulation preparing method and use in preparing medicine for anti-cold thereof
A technology of volatile oil and nepeta, which is applied in the field of preparation of anti-cold medicine, can solve the problems of slow effect, large side effects, and large side effects, and achieve the effects of small dosage, antibacterial and antiviral, and improved stability
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Embodiment 1
[0040] The extraction method of embodiment 1, Schizonepeta volatile oil, its extraction step is:
[0041] (1) Take 3.31 kg of nepeta panicles, add 10 times the amount of water, and steam distill for 6 hours;
[0042] (2) Separation with an oil-water separator to obtain 33.0 g of water-containing Nepeta volatile oil;
[0043] (3) Freeze at -12°C for 24 hours, remove the ice and water, and obtain 31.5 g of nepeta volatile oil.
Embodiment 2
[0044] Embodiment 2, the preparation method of hard capsule of the present invention-Jingan Capsule, its preparation step is:
[0045] (1) Take 31.5g of Nepeta volatile oil, add 8 times the amount of β-cyclodextrin (252g) and 20 times the amount of β-cyclodextrin in distilled water (5.04L), and disperse at a high speed for 30 minutes with a disperser at 30°C ;
[0046] (2) The encapsulation liquid is spray-dried, the air inlet temperature is set to 160°C, and the air outlet temperature is 70°C to obtain the inclusion material and spray dry powder;
[0047] (3) Add 10ml of 95% ethanol to every 250g of spray-dried powder, dry granulate, and fill 1000 capsules, each containing 0.25g, to get final product.
Embodiment 3
[0048] Embodiment 3, the preparation method of soft capsule of the present invention-Qingfei soft capsule, its preparation step is:
[0049] (1) Take 2g of Nepeta volatile oil, add 31.35g of polyethylene glycol-400 and 1.65g of glycerin, and stir for 2 hours at 30°C to disperse the medicinal solution;
[0050] (2) making soft capsules from the dispersed medicine;
[0051] (3) Wash the compressed soft capsules with 75% ethanol, and dry them at 25°C for 72 hours to obtain the final product.
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