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Hemin production process, and health-care composition for making iron and zinc made thereof

A technology of hemin and production process, which is applied in the field of iron supplements, can solve the problems of only high yield, low efficiency, and simultaneous occurrence, and achieve the effect of reducing expenditure and burden, and reducing production costs

Active Publication Date: 2005-02-16
SHANGHAI HONGRU SCI TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its yield only reaches 80%, especially does not mention how through effective raw material control, adopts a kind of preparation process, to meet people's demand to the hemin chloride of different concentration, satisfy the needs of different customers
[0008] At the same time, the traditional method of filtration takes about 4 hours to filter a ton of digestive juice under normal circumstances, and the efficiency is not high
[0009] Existing health-care nutrient solutions for iron supplementation and zinc supplementation cannot achieve simultaneous hemin and zinc supplementation agents (such as zinc gluconate) in a product, and usually iron-deficient patients will be zinc-deficient at the same time, so Firstly, if the consumer must buy two products at the same time, in order to meet the needs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A kind of production technology of hemin, its technology comprises the following steps:

[0030] a) Add 1 / 10 volume of 8% sodium citrate to fresh blood of livestock and poultry animals, centrifuge at high speed for 15-60 minutes, remove serum and fibrin, and obtain red blood cell suspension;

[0031] b) adding 1-3g / 1000ml of sodium chloride into the 60% acetic acid solution, and heating the solution to boiling;

[0032] c) Slowly inject the erythrocyte suspension obtained in a) into the acetic acid solution containing sodium chloride in b), adjust the volume ratio of the erythrocyte suspension to b) the acetic acid solution containing sodium chloride to be 1:4, and digest 0.5 ~1 hour, until the reaction is complete;

[0033] d) press-filtering the mixed solution passed through c) to obtain a solid, which is then washed with hot dilute acetic acid and hot distilled water;

[0034] e) drying the solid obtained in d) to constant weight at 110-130° C. to obtain 80% hemin ...

Embodiment 2

[0036] Repeat Example 1 according to the same steps as described, but the acetic acid solution is 80%, adjust the volume ratio of the erythrocyte suspension and b) the acetic acid solution containing sodium chloride to be 1: 4, and obtain 90% hemin finished product .

Embodiment 3

[0038] Repeat the same steps as described in Example 1, but the acetic acid solution is 90%, adjust the red blood cell suspension and b) the volume ratio of the acetic acid solution containing sodium chloride is 1: 4, to obtain more than 95% hemin finished product.

[0039] In the above process, all the filtrate is recovered and distilled to obtain dilute acetic acid and polypeptide suspension, and the polypeptide suspension is dried and pulverized to obtain polypeptide powder.

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PUM

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Abstract

The invention refers to a kind of iron-adding agent and especially refers to the production technique of the hemin. The technique includes the following steps: a) get rid of the blood serum and fibrin in the fresh blood of livestock and birds for the red cell suspension; b) put the 1-3g / 1000ml sodium chloride into the acetate solution with the thickness between 60% and 100% and heat the solution to between 100deg.C and 110deg.C; c) add the red cell suspension got from the a) to the acetate solution with sodium chloride got from the b) and get the mixed solution; d) filter press the mixed solution got from the c) to get the solid materials and wash them with hot spirit of vinegar and hot distilled water respectively; e) dry the solid materials got from the d) between 110deg.C and 130deg.C to constant weight and then get the turnoff of hemin. If we mix the hemin of the invention with the zinc-adding agent (such as zinc gluconate) in reasonable proportion, we can get the iron-adding and zinc-adding health protection combination.

Description

Technical field: [0001] The invention relates to an iron supplement, especially a production process for hemin. Background technique: [0002] There are two types of iron supplements commonly used by people, non-heme iron supplements and heme iron supplements. [0003] However, long-term use of non-heme iron can easily lead to various side effects, such as nausea, bloating, digestive organ disorders, diarrhea, and constipation. In severe cases, it may even cause excessive iron load in the body, iron accumulation, and iron poisoning. [0004] Therefore, it is generally adopted to take heme iron to supplement the iron element necessary for the human body. It comes from hemoglobin, myoglobin, and other hemoglobins from animal foods. After being digested by gastric acid and protease, the free hemoglobin is directly ingested by the intestinal mucosal cells, and then decomposed into protoporphyrin and iron by heme oxygenase in the cells to be absorbed. The absorption of heme ir...

Claims

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Application Information

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IPC IPC(8): A61K31/555A61P3/02C07F15/02
Inventor 于茂泉官代学
Owner SHANGHAI HONGRU SCI TECH DEV
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