Traditional Chinese medicine for treating aplastic anemia and its preparation process

A technology of aplastic and traditional Chinese medicine, applied in the direction of medical preparations containing active ingredients, blood diseases, drug combinations, etc., can solve the problems of clinical application limitations, poor efficacy, and unsustainable curative effect, and achieve the promotion of hormone receptor affinity in the body , recovery of bone marrow hematopoietic function, promotion of proliferation and differentiation

Inactive Publication Date: 2005-04-06
武汉芄焓药物研发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment of aplastic anemia at home and abroad is nothing more than the following types of drugs: First, androgen and cyclosporin are the most commonly used drugs for the treatment of aplastic anemia today, but both have different degrees. Toxic and side effects have greatly restricted its clinical application
Second, GM-CSF, EPO, IL-3 and other cytokines have been used in the treatment of aplastic anemia in recent years, but the curative effect is not long-lasting, and the price is expensive, so it is not the first choice for treatment
Third

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] Embodiment 1: take raw material (kilogram) by following weight ratio:

[0086] Red ginseng root 25 Astragalus 8 Rehmannia glutinosa 8

[0087] Cuscuta 8 Antler slices 8 Moxibustion tortoise shell 8

[0088] Lycium barbarum 8 Psoralen 8 Cooked aconite 8

[0089] cinnamon 2

Embodiment 2

[0090] Embodiment 2: take raw material (kilogram) by following weight ratio:

[0091] Red ginseng root 30 Astragalus 9 Rehmannia glutinosa 9

[0092] Cuscuta 9 Antler slices 9 Moxibustion tortoise shell 9

[0093] Lycium barbarum 9 Psoralen 9 Cooked aconite 9

[0094] Cinnamon 3

Embodiment 3

[0095] Embodiment 3: take raw material (kilogram) by following weight ratio:

[0096] Red ginseng root 35 Astragalus root 12 Rehmannia glutinosa 12

[0097] Cuscuta 11 Antler slices 11 Moxibustion tortoise shell 11

[0098] Lycium barbarum 10 Psoralen 14 Cooked aconite 9

[0099] Cinnamon 5

[0100] Its preparation process is as follows: according to the weight proportion in the above-mentioned embodiment, ten traditional Chinese medicine raw materials of red ginseng, astragalus, rehmannia glutinosa, dodder, antler slices, moxibustion tortoise shell, medlar, psoralen, cooked aconite and cinnamon are decocted with water. Twice, adding 7 times the weight of the raw material to decoct for 45 minutes each time, and merging the filtrates decocted twice. The combined filtrate is then concentrated to a relative density of 1.15 (measured at a temperature of 90° C.), adding ethanol to the filtrate with an alcohol content of 55%, ethanol precipitation for more than 24 hours, reclaimi...

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PUM

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Abstract

The invention discloses a medicinal Chinese medicine for curing regenerative obstructive anaemia and its preparing technique, prepared in proportion of red ginseng tails, Radix astragali, Radix rehmanniae preparata, dodder seed, alter slice, moxibustion tortoise plastron, medlar, Malaytea Scurfpea Fruit, Prepared Common Monkshood Daughter Root, and cinnamon. And the preparing technique: decocting the above ten raw materials twice and combining the two filtrates; then concentrating, alcohol-depositing, cooling to room temperature and making into cream; drying the cream and then making powder spraying and filling into capsules; or adding dextrin or starch to the cream to make into soft material, and finally screening and drying the soft material to make into electuary or tablets. It can not only regulate mediation disorder of human immunity, stimulate the hemopoiesis recovery of human marrow, and have remarkable curative effect on the regenerative obstructive anaemia but also has considerably good curative effect on other refractory anaemias, as well as the symptoms caused by various reasons, such as marrow inhibition, blood cell reduction, etc. And it almost has no toxicity and side effect, safe and reliable, low-cost.

Description

technical field [0001] The invention relates to a kidney-tonifying and marrow-reinforcing medicament prepared from Chinese herbal medicines, in particular to a traditional Chinese medicine for treating aplastic anemia and a preparation process thereof. Background technique [0002] Aplastic anemia, as a disease of hematopoietic pararegulatory hyperactivity, has become a common disease of the blood system with great harm. Clinically, it is mainly chronic, protracted, and extremely difficult to treat. So far, there is no ideal drug, which makes clinicians feel difficult. Especially in recent years, with the emergence of the national house decoration upsurge, people are more and more likely to be in contact with harmful chemical decoration materials, resulting in an increase in the incidence of aplastic anemia in my country year by year, and there is a trend of younger patients, so There is an urgent need for a safe and reliable new drug for treatment. ...

Claims

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Application Information

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IPC IPC(8): A61K9/14A61K9/20A61K9/48A61K35/586A61P7/06
Inventor 徐靖
Owner 武汉芄焓药物研发有限公司
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