Preparation for improving bioavailability and medicine effect for treating gynecopathy and preparing method

A technology for gynecological diseases and availability, which is applied to sexual diseases, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems that sugar-coated tablets should not be used by patients with sugar, are easily contaminated by microorganisms, and take a large amount of patients. Achieve the effect of enhancing peritoneal macrophage function, enhancing physical strength, and improving immune function

Active Publication Date: 2005-05-18
GUANGDONG LUOFUSHAN SINOPHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The original dosage form is a traditional sugar-coated tablet, and the patient takes a large amount
And because there are more protein nutrients in the original prescripti

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Embodiment 1: the weight ratio of the medicinal materials used is:

[0091] Chunpi 300g Schisandra 50g Phellodendron 350g

[0092] Tortoise shell 230g Poria cocos 350g donkey-hide gelatin 110g Chinese yam 350g

[0093] Its preparation step comprises the following steps:

[0094] Step 1: Take the Chinese toon skin and add 6 times the amount of water to decoct twice, each time for 2 hours, combine the decoction, filter, concentrate the filtrate to an appropriate amount (relative density 1.20 at 40°C), add ethanol to make the alcohol content about 50%, stand still, filter;

[0095] Step 2: take the Cortex Phellodendri of said share and extract it three times with 85% ethanol under reflux, each time for 1.5 hours, combine the extracts, and filter;

[0096] Step 3: get the poria cocos of described share with 60% ethanol, the schisandra chinensis of described share and the Chinese yam of described share use 45% ethanol to carry out percolation method under flow extract and...

Embodiment 2

[0099] Embodiment 2: the weight ratio of the medicinal materials used is:

[0100] Toon bark 363g Schisandra 64g Phellodendron 363g

[0101] Tortoise shell 242g Poria cocos 363g donkey-hide gelatin 120g Chinese yam 363g

[0102] Its preparation step comprises the following steps:

[0103] Step 1: Take the said portion of Chinese toon skin and add 8 times the amount of water to decoct twice, each time for 2 hours, combine the decoction, filter, concentrate the filtrate to an appropriate amount (relative density of 1.25 at 40°C), add ethanol to make the alcohol content about 50%, stand still, filter;

[0104] Step 2: take the Cortex Phellodendri of said share and extract it three times with 85% ethanol under reflux, each time for 1.5 hours, combine the extracts, and filter;

[0105] Step 3: get the poria cocos of described share with 60% ethanol, the schisandra chinensis of described share and the Chinese yam of described share use 45% ethanol to carry out percolation method ...

Embodiment 3

[0108] Embodiment 3: the weight ratio of the medicinal materials used is:

[0109] Chunpi 426g Schisandra 78g Phellodendron 376g

[0110] Tortoise shell 254g Poria cocos 376g donkey-hide gelatin 130g Chinese yam 376g

[0111] Its preparation step comprises the following steps:

[0112] Step 1: Take the said portion of Chinese toon skin and add 15 times the amount of water to decoct twice, each time for 2 hours, combine the decoction, filter, concentrate the filtrate to an appropriate amount (relative density 1.35 at 40°C), add ethanol to make the alcohol content approx. 50%, stand still, filter;

[0113] Step 2: take the Cortex Phellodendri of said share and extract it three times with 85% ethanol under reflux, each time for 1.5 hours, combine the extracts, and filter;

[0114]Step 3: get the poria cocos of described share with 60% ethanol, the schisandra chinensis of described share and the Chinese yam of described share use 45% ethanol to carry out percolation method unde...

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PUM

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Abstract

The gynecopathy treating medicine preparation with raised bioavailability and treating effect is prepared with seven kinds of Chinese medicinal materials, including heaven tree bark, schisandra, phellodendron bark, tortoise plastron, tuckahoe, etc. in certain proportion. The extract of the said medicine material, stuffing, disintegrating agent and lubricant are produced into dispersed tablet; the extract of the said medicine material, dispersing medium, suspension assistant and preservative are prepared into soft capsule; or, the extract of the said medicine material, stuffing, disintegrating agent and lubricant are prepared into capsule. The dispersed tablet, the soft capsule and the capsule are used in treating chronic pulvic infection, and have high curative effect and short treating period.

Description

technical field [0001] The invention relates to a preparation and a preparation method for improving bioavailability and drug efficacy for treating gynecological diseases. technical background [0002] Gynecological anti-discharge tablets have the effect of clearing away heat and dampness, astringent and anti-discharge, and are used for damp-heat type red and white leucorrhea caused by chronic cervicitis, endometritis, and vaginal mucositis. Pharmacological studies have shown that Fuke Zhidai Tablets have: [0003] 1. Anti-pathogenic microorganism effect. It has good antibacterial effect on Staphylococcus aureus, Streptococcus, Pseudomonas aeruginosa, Escherichia coli and Candida albicans. [0004] 2. Anti-inflammatory effect. It can reduce capillary permeability, inhibit inflammatory exudation and connective tissue, and reduce inflammatory response. [0005] 3. Improve immune function and enhance physical strength. It can increase the weight of rat thymus and spleen, e...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61K35/36A61K35/586A61P15/00
Inventor 叶耀良廖志钟
Owner GUANGDONG LUOFUSHAN SINOPHARM
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