Compound tornado drop pills
A croissant and compound technology, which is applied in pill delivery, medical formula, nervous system diseases, etc., can solve the problems of hepatic and intestinal first-pass effect bioavailability, long dissolution time limit, and expensive products, so as to be beneficial to labor protection and environmental protection , avoid gastrointestinal irritation symptoms, improve the effect of bioavailability
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[0034] Now with the test of several groups of specific examples and the results thereof, the preparation method of the compound Yangjiao dripping pill of the present invention will be further described.
[0035] Group 1: Tests with a single matrix
[0036] [formula]
[0037] 1. Raw materials: dry powder containing four active ingredients of traditional Chinese medicines such as horns, chuanxiong, angelica, and aconitum extracted according to the method provided in [Preparation of extracts of horns, chuanxiong, angelica, and aconitum (hereinafter collectively referred to as drug extracts);
[0038] 2. Substrate: polyethylene glycol 2000、4000、6000、8000、10000、20000 , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;
[0039] 3. Proportion (in g or kg, in parts by weight): drug extract: matrix = 1:1-1:9.
[0040] [test results]
[0041]...
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