8 results about "Nerves pain" patented technology

The utility model discloses an acupoint treatment electric needle for relieving neuropathic pain. The acupoint treatment electric needle comprises a treatment needle rod and a connecting mechanism, the upper end of the treatment needle rod is sleeved with a power supply cylinder; the connecting mechanism comprises elastic pieces, locking openings and locking blocks, the elastic pieces are evenly and fixedly connected to the lower end of the power supply cylinder, the locking openings are evenly formed in the middle of the treatment needle rod, the lower ends of the inner surfaces of the elastic pieces are fixedly connected with the locking blocks, and the locking blocks are connected with the transversely adjacent locking openings in a clamped mode. The connecting mechanism further comprises an external thread and a fastening nut, the external thread is arranged on the outer surface of the whole formed by the elastic piece and the power supply cylinder, the fastening nut is connected to the middle of the external thread in a threaded mode, a cavity is formed in the treatment needle rod, and an electrode bar is arranged in the cavity. Rapid and stable connection of the power supply cylinder and the treatment needle rod can be realized, and unstable connection of the power supply cylinder and the treatment needle rod caused by an operation mode in a use process is avoided.

The invention discloses a method for detecting the pain level in combination with neural activity and detection equipment, the detection equipment comprises a detection deck chair support, a buffer structure and a detection structure, the detection structure and the buffer structure are installed on the detection deck chair support, and the invention relates to the technical field of neuropathic pain detection. Through electroencephalogram spectrum analysis, electrocardio variability monitoring, pupil dynamic tracking and enphalin blood concentration detection, a pain related biomarker database is constructed, and compared with a traditional subjective scale, the objective index association degree is remarkably improved; the original arc-shaped guide rail buffer system and the rotary air bag fixing devices effectively absorb detection shaking, and are matched with the four pairs of rotary air bag fixing devices, so that the human engineering impact is attenuated under the low-frequency vibration working condition of below 10Hz.

Methods, systems and devices are provided to stimulate the vestibular system in such a way as to alleviate post-infection symptoms of COVID-19. A device with one or more electrodes placed over a subject's scalp provides vestibular nerve stimulation (VeNS) to the vestibular nerve, which is then carried into the vestibular nucleus in the brainstem to alleviate post-infection symptoms of COVID-19 related to the vestibular system, including dizziness, fatigue, malaise, headache, nerve pain, insomnia and sleep problems, anxiety, depression and difficulty concentrating. The characteristics of the stimulation signal and duration of the treatment are configured to allow the treatment to be delivered at the onset of one or more symptoms or at regular daily intervals alleviate the post-infection symptoms immediately or over a longer period of time.

The present application relates to S ) -2-((3-((benzo[ d [1,3]dioxolane-5-oxomethyl)benzyl)-amino)propanamide, to pharmaceutical compositions containing it, and to the use of this crystalline form for the preparation of a medicament for the prevention and / or treatment of pain (e.g. neuropathic pain, including chronic neuropathic pain or neuropathological pain).

This disclosure describes a cannabinoid-based nanoplatform for treating shingles, designed to enhance bioavailability and controlled release of active ingredients. The composition includes cannabinoids like cannabidiol (CBD) and cannabigerol (CBG), alongside flavonoids, polyphenols, and alkaloids, in oral and topical formulations. The oral capsule combines cannabinoids with polyphenols and flavonoids to provide systemic anti-inflammatory, antiviral, and neuroprotective effects, particularly for nerve pain and inflammation, including postherpetic neuralgia. The topical cream includes cannabinoids, capsaicin, and aloe vera, offering localized relief from pain, itching, and rash. The method targets both systemic and localized symptoms during the acute phase of shingles, aiming to inhibit varicella-zoster virus replication, disrupt viral assembly, and prevent viral release, while also providing immune modulation and anti-inflammatory benefits. The nanoplatform uses nano-emulsification techniques, producing particles smaller than 200 nm to ensure optimal delivery and therapeutic efficacy, offering comprehensive relief for shingles symptoms.

The application discloses a gamma-aminobutyric acid derivative, a pharmaceutical composition and application, and relates to a gamma-aminobutyric acid derivative, an enantiomer, a racemate or a pharmaceutically acceptable salt thereof, a compound with a structural formula as shown in formula I: the compound provided by the application has a strong inhibitory effect on the combination of a human voltage-gated calcium ion channel alpha2delta subunit and 3 H] gabapentin, an IC 50 value of 15.2 nM is measured, and the compound can be used for preparing a therapeutic drug for chronic nerve pain, epilepsy and anxiety.

Improved nerve regeneration scaffolds are disclosed, which include a plurality of modified nanotube yarn bundles disposed of within the scaffold lumen. The modified nanotube yarn bundles have enhanced hydrophilicity and water absorption. They are separated by distances to form channels corresponding to nerve fiber diameters to be occupied by regenerative nerve tissues. The channel walls have gaps between the yarn bundles for enhanced permeability. The scaffolds have reduced inflammatory infiltration and rejection response and support individual nerve fiber regrowth with a reduced likelihood of undesirable outcomes, such as nerve pain or reduced nerve function.

The invention relates to the technical field of biological medicine, in particular to a traditional Chinese medicine composition for treating herpes zoster, which comprises lithospermum, cicada slough, honeycomb, rhizoma cimicifugae, kudzuvine root, red paeony root, cyrtomium rhizome, folium isatidis, honeysuckle, fructus forsythiae, centipede and raw liquorice. The 12 traditional Chinese medicines in the traditional Chinese medicine composition are combined into the formula, so that the traditional Chinese medicine composition has the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, dispelling wind and promoting eruption, clearing away in-vivo viruses and free radicals through oral administration and promoting repair of nerve electrophysiology and myelin sheaths, directly acts on herpes skin lesion parts through external application, and has the effects of detoxifying, relieving pain, preventing skin infection and promoting skin lesion repair. Internal and external treatment has positive effects on skin symptoms, pain and virus activity of herpes zoster, local blood circulation is improved, and neuropathic pain is relieved.