Tumor tomography method and device with phonochemistry luminance provoking function by focused ultrasound

Abstract

The invention relates to a sonochemistrical luminous tomography method for tumour, which is that after distributing of sonosensitizer in tumour group, generating active oxygen-derived free radicals by scanning point by point and sensitizing used focusing ultrasound; translating the active oxygen-derived free radicals generated during sonosensitizing process real time and directly by chemical luminous agents into photons and radiating out; based on that, simulating the imaging of tumour group by optics detection technique. The apparatus comprises ultrasound producing groupware, light receiving groupware, A / D converter, triaxiality scanning device and computer; wherein ultrasound producing groupware and triaxiality scanning device link to computer, light receiving groupware and A / D converter link to computer in turn. The invention combines strong penetrating ability of focusing ultrasound to body and the advantages of high sensitivity and intactness of optics imaging, brings no radioactive damage to organism.

Description

technical field [0001] The present invention relates to medical tomography and medical devices. In more detail, a focused ultrasound-induced acoustochemiluminescence method for tumor tomography. [0002] The invention also relates to a device for carrying out the above-mentioned method. Background technique [0003] Tumor is a common and frequently-occurring disease, among which malignant tumor is a kind of disease that seriously endangers human health, and its mortality rate ranks second only to cardiovascular disease. In view of the fact that the etiology and pathogenesis of tumors are not clear at present, the treatment methods related to tumors cannot fundamentally solve the problem. Therefore, the diagnosis of malignant tumors in medicine must rely on the comprehensive application of clinical diagnosis, instrumental diagnosis (such as CT, MRI, B-ultrasound, etc.), laboratory (tumor markers, genetic testing, etc.) The means to make a correct judgment, the diagnosis co...

AI Technical Summary

Problems solved by technology

In view of the fact that the etiology and pathogenesis of tumors are not clear at present, the treatment methods related to tumors cannot fundamentally solve the problem.

Therefore, the diagnosis of malignant tumors in medicine must rely on the comprehensive application of clinical diagnosis, instrumental diagnosis (such as CT, MRI, B-ultrasound, etc.), laboratory (tumor markers, genetic testing, etc.) The means to make correct judgments, the cost of diagnosis is extremely high, and early tumor diagnosis cannot be achieved

[0004] Biomedical photonics imaging technology has the advantages of no damage to the human body, high sensitivity, and functional imaging, but the disadvantages are small penetration depth and strong biological autofluorescence interference

On the other hand, the penetration performance of ultrasound in the body is very good, but the current imaging technology based on ultrasound (such as B-ultrasound) can only do interface reflection imaging, and the sensitivity is low

For the optical imaging of tumor tissue, the laser-induced drug fluorescence imaging method is generally used. Because it uses a short-wavelength excitation light source, it has problems such as tissue autofluorescence interference and small penetration depth that cannot be overcome. In addition, when using this method, the Skin phototoxic side effects will inevitably occur, which will cause greater damage to patients

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