Chinese medicine preparation and set of apparatuses thereof

Abstract

A process for preparing Chinese medicines includes such steps as extracting, solid-liquid separating, heating for sterilizing, and vacuum concentrating. Its complete set of apparatuses is composed of extractor, solid-liquid separator, sterilizer and vacuum concentrating unit. Its advantages are high automation level, productivity and quality of product, and low energy consumption.

Description

technical field [0001] The invention belongs to the technical field of continuous production technology for preparing traditional Chinese medicine raw materials into thick paste products or dry powder finished products, and also relates to the technical field of complete equipment structure for this technology. Background technique [0002] The existing traditional Chinese medicine preparation technology usually completes the extraction, concentration and drying of traditional Chinese medicine in different sections, and cannot directly produce finished materials continuously. Even if it is divided into sections, it uses manual or semi-automatically controlled equipment that requires manual assistance. For example, the extraction process uses traditional equipment such as water-liquid decoction pots or stainless steel extraction tanks, or adopts percolation extraction processes, etc. These extraction equipment and processes basically retain the characteristics of traditional ...

AI Technical Summary

Problems solved by technology

The tilting reaction pot has a high evaporation temperature, the material is heated for a long time, and the heat-sensitive components are easy to coke. The large amount of water vapor evaporated will easily cause mold to grow in the plant and equipment, which seriously affects the sanitation of the pharmaceutical production environment; the vacuum concentration reaction pot cannot accurately control the concentration process. The concentration effect is poor; the thin-film concentration and evaporation equipment has a high evaporation temperature, and the evaporation temperature and feed volume cannot be automatically controlled, so coking often occurs; double-effect and three-effect external circulation concentration and evaporation equipment have different effects The density cannot be detected automatically, manual operation is required for feeding and discharging materials, there is no automatic control system for temperature, pressure and vacuum, and the vacuum and condensation system consumes a lot of energy

In the commonly used drying methods of concentrated liquid medicine, vacuum drying, freeze drying and hot air circulation oven have unsatisfactory drying effects, not only uneven drying, easy caking, low efficiency and long drying time, but also manual operation is required for feeding and discharging materials. , easy to be polluted, and the operating environment is harsh; the fluidized drying bed is easy to make the dried material agglomerate and the noise is loud

Freeze-drying and vacuum drying require large-scale equipment, and it is difficult to adopt continuous production steps, and the production method is troublesome and laborious; at the same time, after freeze-drying or vacuum freeze-drying, necessary additional steps such as grinding and homogenization make The production process has become more cumbersome; some manufacturers currently use the spray drying method, but the process and equipment control level is low, the product quality is poor, and it is difficult to handle the viscous extract, which has low drying strength and large return material

In the existing traditional Chinese medicine preparation method, the separation of the dregs and the liquid medicine is not complete, and the liquid concentrated in the vacuum contains more impurities, which not only wears and blocks the equipment pipeline, but also greatly reduces the quality of the finished material, and the sterilization is not sufficient , so that the average bacterial content of the final finished product material is too high, and it is difficult to meet the requirements of GMP for the bacterial content of pharmaceuticals

Moreover, the existing concentration treatment generally only proceeds to the subsequent drying treatment after one concentration, and directly produces dry Chinese medicine granules or powder, but the medicinal liquid after one concentration is difficult to be directly used in the production of extracts due to the low concentration rate. products, resulting in a single variety of finished product materials, which is difficult to meet the requirements of product diversity

In addition, due to the low level of automatic control of the existing equipment and the inconvenient cleaning, the quality of the produced products is unstable and the production efficiency is low

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