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Compound preparation for anti-pregnancy by kiilling sperm and sterilizing and preparing method

A compound preparation, sterilization and disinfection technology, applied in the direction of antibacterial drugs, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as poisoning shock, allergic reactions, irregular bleeding, etc., achieve strong antibacterial effect, easy to use , less toxic and side effects

Inactive Publication Date: 2006-03-08
广东同德药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Currently commonly used contraceptive methods are oral contraceptives and external barrier contraception. Condoms, vaginal diaphragms, cervical caps, contraceptive sponges, and birth control all have certain deficiencies in use. Oral contraceptives often have endocrine-interfering effects and cause nausea. , vomiting, and even irregular vaginal bleeding and other side effects limit its scope of use; condoms are currently the most widely used male contraceptive tool, but some people may experience allergic reactions or discomfort, and the rupture rate is reported at 1%-12% The rate of slippage during sexual intercourse is 6%; the vaginal septum is a soft rubber cap that is put into the vagina before intercourse to cover the cervix and posterior fornix, but because the edge of the septum cannot be tightly sealed with the vaginal wall, the failure rate is 1.6%- It varies from 9.8%; the cervical cap is a rubber barrier contraceptive tool similar to the diaphragm, and the doctor must choose the size and guide the application method during application, and the failure rate is 5%-18%; the contraceptive sponge is a spermicide It is a circular elastic block made of polyurethane material, which has the functions of absorbing semen, immobilizing sperm and barrier contraception, but there are reports of toxic shock syndrome caused by vaginal sponge fragments remaining in the vagina

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] Nano silver 0.01kg Octoxynol 10kg Propylene 30kg

[0083] Isobutane 70kg Sodium Lauryl Sulfate 5kg Triethanolamine 10kg

[0084] Glycerol 5kg Polyethylene Glycol-400 10kg Polysorbate-60 10kg

[0085] Distilled water 500kg

[0086] The particle size of nano silver is 50 nanometers;

[0087] Preparation method: Mix distilled water, sodium lauryl sulfate, triethanolamine, glycerol, polyethylene glycol-400, polysorbate-60 at room temperature and stir evenly, add nano-silver and octoxynol and stir evenly , fill the filtrate, 54 grams per bottle, seal, then fill the propellant propylene butane and isobutane, add a cap, and pack to get final product.

Embodiment 2

[0089] Nano silver 0.05kg Nonoxynol ether 20kg Dimethyl ether 150kg

[0090] Sodium Lauryl Sulfonate 15kg Amyl Alcohol 5kg Polysorbate-80 15kg

[0091] Propanol 25kg Ethanol 5kg Distilled water 850kg

[0092] The particle size of nano silver is 100 nanometers;

[0093] Preparation method: Mix distilled water, sodium dodecylsulfonate, pentanol, propanol, ethanol, polysorbate-80 at room temperature and stir evenly, add nano-silver and nonoxynol ether, stir evenly, fill the filtrate , 51 grams per bottle, sealed, then filled with propellant dimethyl ether, capped, and packaged.

Embodiment 3

[0095] Nano silver 0.1kg Menthoxylate 2kg Difluoroethane-152a 100kg

[0096] Difluorodichloromethane-12 200kg α-monoalkyl glyceryl ether 25kg Hexanol 80kg

[0097] Polyoxyethylene polyoxypropylene copolyether 15kg Isopropyl alcohol 80kg Propylene glycol 15kg

[0098] Sorbitan Monostearate-80 45kg Deionized Water 330kg

[0099] The particle size of nano silver is 1 nanometer;

[0100] Preparation method: deionized water, polyoxyethylene polyoxypropylene copolyether, α-monoalkyl glyceryl ether, hexanol, propylene glycol, isopropanol, sorbitan monostearate-80 Mix and stir evenly, add nano-silver and menthenyl ether, stir evenly, and filter. Fill the filtrate to 42 grams per bottle, seal it, and then fill it with propellant difluoroethane-152a and difluorodichloromethane-12, cap it, and pack it.

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PUM

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Abstract

The present invention relates to a compound preparation for bactericidal sterilization and spermicidal contraception and its preparation method. Said compound preparation includes broad-spectrum antimicrobial, spermicide for contraception, water and auxiliary material. Said compound preparation adopts vaginal medication method, so that it is fase and reliable. Said invention also provides its preparation method and concrete steps.

Description

technical field [0001] The invention relates to a compound preparation for spermicide, anti-pregnancy and sterilization, in particular to a foam agent for spermicide, anti-pregnancy and sterilization and a preparation method thereof. Background technique [0002] Family planning is the basic national policy of the country, and the improvement and popularization of family planning appliances and equipment is an important technical support for the realization of this national policy. The development of safe, effective, simple, less side effects, beneficial to reproductive health, and the masses are willing to accept Family planning appliances and devices are the development trend of family planning products. [0003] Currently commonly used contraceptive methods are oral contraceptives and external barrier contraception. Condoms, vaginal diaphragms, cervical caps, contraceptive sponges, and birth control all have certain deficiencies in use. Oral contraceptives often have endo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/00A61K33/38A61P15/02A61P15/18A61P31/04
Inventor 周旭明
Owner 广东同德药业有限公司
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