Chinese medicinal gel formulation, its preparation process and quality control method
A technology of gel preparation and traditional Chinese medicine, which is applied to the quality control of the gel preparation, the field of traditional Chinese medicine gel preparation and its preparation, and can solve the problems of prolonging the residence time of the drug in the cornea, poor drug absorption, and prolonging the action time. Achieve the effect of reducing gastrointestinal irritation, reducing other side effects, and not polluting clothes
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Example Embodiment
[0040] Example 1:
[0041] Prescription: pearl liquid 20ml borneol 1.0g
[0042] Preparation method: Soak 2g of carbomer in 500ml of water for injection, leave it overnight until the matrix is fully swelled, add pH adjusters boric acid and borax into it, stir evenly, control the pH value to 5-7, and then add the antibacterial agent phenoxy Dissolve ethanol in 200ml of hot water at 80°C, let it cool, add pearl liquid, borneol ethanol solution, and glycerin, mix well, then mix the above two liquids evenly, add water for injection to 1000ml, autoclave sterilization, and stir well , Coarse filtration and then fine filtration to obtain a transparent gel, let it cool, and package it to make a finished product.
Example Embodiment
[0043] Embodiment 2:
[0044] Prescription: pearl liquid 20ml borneol 1.0g
[0045] Preparation method: Soak 2g of hypromellose in 500ml of water for injection, leave it overnight until the matrix is fully swelled, then dissolve the antibacterial agent phenoxyethanol in 200m of hot water at 180°C, let it cool, and add pearl liquid and borneol. Ethanol dissolving solution, boric acid, borax, glycerin, mix evenly, then mix the above two liquids evenly, add water for injection to 1000ml, stir well, autoclave, first coarsely filter and then finely filter to obtain a transparent gel, let it cool , packaged into finished products;
Example Embodiment
[0046] Embodiment three:
[0047] Prescription: pearl liquid 20ml borneol 1.0g
[0048] Preparation method: first soak 3g of chitosan in 500ml of water for injection, add boric acid to dissolve it, then dissolve the antibacterial agent phenoxyethanol in 200ml of hot water at 80°C, let it cool, add pearl liquid and borneol to dissolve in ethanol liquid, boric acid, borax, glycerin, mix evenly, then mix the above two liquids evenly, add water for injection to the full amount, autoclave sterilization, stir well, first coarsely filter and then finely filter to obtain a transparent gel, let cool, and package finished product;
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