Levamlodipine oral disintegrating tablet formulation and its preparing method

Abstract

The present invention discloses a levoamlodipine oral disintegrating tablet preparation and its preparation method. It is made up by using levoamlodipine or its active salt as main medicine, using other ingredients as auxiliary material and adding stabilizing agent, for example citric acid, ascorbic acid, lactic acid, benzenesulfonic acid or maleic acid through a certain preparation process. Besides, said invention also provides the concrete steps of its preparation process.

Description

technical field

[0001] The invention relates to a drug orally disintegrating tablet for treating hypertension and angina pectoris, in particular to a levoamlodipine orally disintegrating tablet preparation and a preparation method thereof. technical background

[0002] Cardiovascular disease is the number one killer threatening human health, and hypertension is one of the most common diseases. Epidemiological studies show that there are currently 600 million hypertensive patients in the world, and the prevalence of hypertension is about 10%. The national prevalence rate of hypertension is about 12%, and it is as high as 20% in some developed countries in Europe and America. According to national statistics, the number of hypertensive patients in my country has reached 100 million, and more than 3 million people are newly added every year. Hypertension will be a major public health problem facing our country. Complications of hypertension such as s...