Freeze-drying powder injection containing red-rooted salvia safflower
A technology of freeze-dried powder injection and red jelly, which is applied in the field of medicinal powder injection, can solve the problems of unclear active ingredients, affecting the effectiveness and safety of Danhong injection, and the comprehensive curative effect is not obvious, so as to improve hemodynamics The effect of science, easy quality control, and high comprehensive curative effect
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Embodiment 1
[0041] Preparation of Salvia miltiorrhiza extract: take 1 kg of salvia miltiorrhiza, soak in 8 kg of 85% ethanol for 24 hours, grind, filter, then soak twice with 8 kg of 80% and 70% ethanol, each time for 12 hours, combine the soaking liquid, filter , decolorized with 0.4% activated carbon, passed through a 80-140 mesh 2cm-thick short silica gel column, concentrated under reduced pressure at 25-50mmHg to a specific gravity of 1.15-1.25, and freeze-dried to obtain 0.002 kg of active ingredients containing 48.2 % more than Danshen extract.
[0042] Safflower pigment: can be purchased from specialized manufacturers.
Embodiment 2
[0044] Danhong freeze-dried powder injection, formula:
[0045] Danshen Extract 125g
[0046] Saffron 75g
[0047] Mannitol 100g
[0048] Process: Under the condition of 10,000 grades, dissolve the above ingredients together in water for injection, after decolorization, add water for injection to dilute to the required volume of 2000ml, filter, and filter the filtrate through filter paper and 0.4μm filter membrane. , under the condition of grade 100, filter with a filter membrane below 0.2 μm, send the fine filtrate into the sub-packer, pack in 2ml per tube, cover with a slotted cover, and send it to a freeze-vacuum dryer, and quickly cool to -38 ℃~-40℃, 2-3 hours, gradually and slowly raise the temperature to 35℃~45℃ (about 10 hours), plug the lid tightly, take out the product, tie the cover, pack, inspect and pass, and make 1000 pieces of 200mg specifications Danhong freeze-dried powder injection.
Embodiment 3
[0050] Danhong freeze-dried powder injection formula:
[0051] Danshen Extract 100g
[0052] Safflower pigment 100g
[0053] Amino Acid 150g
[0054] Using the process provided in Example 2, 1000 Danhong freeze-dried powder injections with a specification of 200 mg were prepared.
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