Sustained release Brufen having magnetic super-molecular inserting layer structure and its prpen. method

A supramolecular intercalation and slow-release technology, which is applied in the direction of organic active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, can solve the problems of non-magnetic supramolecular intercalation ibuprofen sustained-release dosage reports, etc. Achieve the effect of improving bioavailability, reducing unpleasant taste, and improving targeting
CN1947700AInactive Publication Date: 2007-04-18BEIJING UNIV OF CHEM TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BEIJING UNIV OF CHEM TECH
Publication Date
2007-04-18
Estimated Expiration
Not applicable · inactive patent
Patent Text Reader

Abstract

A slow-release ibuprofen with magnetic super-molecular intercalated structure, controllable release speed, high magnetic dispersity, and high magnetic target effect is prepared from spinel, anionic laminated material LDHs, and alkaline solution of ibuprofen through intercalating assembling.
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Description

technical field

[0001] The invention belongs to the technical field of magnetic sustained-release agents, in particular to a sustained-release ibuprofen with a magnetic supramolecular intercalation structure and a preparation method thereof, in particular to a sustained-release ibuprofen with a magnetic supramolecular intercalation structure and an assembly method thereof . Background technique

[0002] Magnetic slow-release drugs are a kind of drugs that integrate magnetism and controlled release. When such drugs are used in the body, the magnetic field effect outside the body can guide the drug to move and concentrate in the body, and realize the controlled release of the drug. Therefore, such drugs are mainly used as carriers of anticancer drugs. Animal experiments and clinical observations have proved that magnetic drugs have a definite effect of inhibiting the growth of cancer cells, shrinking tumors of patients, and improving subjective symptoms.

[0003] Existing mag...

Claims

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