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1 results about "Release modulator" patented technology
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A release modulator, or neurotransmitter release modulator, is a type of drug that modulates the release of one or more neurotransmitters. Examples of release modulators include monoamine releasing agents such as the substituted amphetamines (which induce the release of norepinephrine, dopamine, and/or serotonin) and release inhibitors such as botulinum toxin A (which inhibits acetylcholine release by inactivating SNAP-25, thereby preventing exocytosis from occurring).
This invention belongs to the field of pharmaceutical technology, specifically relating to an injectable sustained-release composition, its preparation method, and its application. Through extensive research, this invention unexpectedly discovered that adding specific release modifiers can significantly slow down the early release rate of drugs. Furthermore, there is a synergistic effect between specific release modifiers and specific structure modifiers, which can effectively improve the sustained-release performance of the composition and significantly reduce the coefficient of variation among individual animals.