Medicinal composition of milkvetch root, chinaroot greenbrier and Hong Jingtian and its making method

A composition, technology of Rhodiola rosea, applied in the field of medicine

Inactive Publication Date: 2007-06-20
海安江理工技术转移中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no report on the preparation of drugs for improving brain function by using the interaction of astragalus or its extracts, rhodiola or its extracts, sarsaparilla or its extracts, and compatible prescriptions

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0165] The preparation and identification and content determination of the total saponins of astragalus of embodiment 1

[0166] Preparation of Total Astragalus Saponins

[0167]Take 50kg of Radix Astragali medicinal material, add water and decoct three times, 1.5 hours each time, add 10 times the amount of water for the first time, and 8 times the amount for the second and third times, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.20-1.25 (60 ℃), with ethanol precipitation treatment for 2 times, the alcohol content in the solution for the first time is 75%, and the second time is 85%, each time it is refrigerated and placed, and the ethanol is recovered and concentrated to the equivalent of 10g of the original medicinal material per 1ml, and added to On the treated macroporous adsorption resin column, wash the column with 2 times the volume of water, then elute with 4 times the volume of 70% ethanol, collect the eluate, concentrate u...

Embodiment 2

[0186] Example 2 Preparation, Identification and Content Determination of Astragalus Polysaccharide

[0187] Preparation of astragalus polysaccharide

[0188] Take the Radix Astragali medicinal material, add 7 times the amount of 70% ethanol to extract twice, each time for 2 hours, discard the extract, take the dregs and add water to extract twice, combine the extract, concentrate until the ratio of the volume of the extract to the raw medicinal material is 1.05: 1. Add ethanol to precipitate to make the alcohol content reach 70%, filter to obtain a precipitate, wash the precipitate with 70% ethanol, dissolve it with an appropriate amount of water, filter, pass the filtrate through a macroporous resin, elute with water, collect the washing liquid, and put Concentrate the washing solution until the ratio of the volume of the medicinal solution to the medicinal material is 1:2.5, add ethanol to make the alcohol content reach 70%, and obtain a precipitate, wash and dehydrate th...

Embodiment 3

[0201] Preparation and Identification and Content Determination of Example 3 Rhodiola Rosea Extract

[0202] Preparation of Rhodiola Rosea Extract

[0203] Take 20kg of Rhodiola rosea medicinal material, grind it into coarse powder, add 70% ethanol to reflux and extract three times, each time for 1.5 hours, combine the extracts, filter, recover the ethanol from the filtrate to contain 1g of raw medicinal material per 2ml, and degrease with 2 times the amount of petroleum ether , discard the petroleum ether solution, extract with n-butanol saturated with water, concentrate under reduced pressure to a thick paste, add to the pre-treated macroporous resin, elute with water and different concentrations of ethanol in turn, and recover ethanol under reduced pressure to relative The density is 1.03~1.06 (60°C), and it can be obtained by spray drying.

[0204] Three batches of Rhodiola rosea extracts were prepared respectively, and the yields are shown in Table 2-3.

[0205] Ident...

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Abstract

A Chinese medicine for improving cerebral function and preventing cerebra ischemic or anoxic injury, senile dementia and vascular dementia is prepared from astragalus root, rhodiola root and Chinaroot greenbrier rhizome or their extracts. Its preparing process is also disclosed.

Description

1. Technical field [0001] The invention belongs to the technical field of medicine, and relates to a pharmaceutical composition mainly made of astragalus or its extract, rhodiola rosea or its extract, and sarsaparilla or its extract, a preparation method thereof and a preparation method for improving brain function. functional medicine applications. 2. Background technology [0002] Brain dysfunction includes brain tissue ischemia or hypoxic injury, memory impairment, dementia, etc. Brain tissue is very sensitive to ischemia and hypoxia. With the aging trend of society and the prolongation of life expectancy, the incidence of ischemic cerebrovascular disease has increased significantly, seriously endangering human health and bringing heavy burdens to society and families. Cognitive dysfunction caused by cerebral ischemia and reperfusion has also received increasing attention. Memory impairment includes memory loss and hypomnesis etc. Dementia is a common senile disease, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K31/715A61P9/10A61P25/00
Inventor 黄振华
Owner 海安江理工技术转移中心有限公司
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