Elemene externally-applied preparation and its use

An external preparation, technology of elemene, applied in the field of preparation and preparation of elemene

Inactive Publication Date: 2007-06-20
谢瑞钢
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] After searching domestic and foreign patent documents, no patent documents were found about elemene using hyaluronic acid, ethanol and medicinal bases for preparation research, nor did we find about elemene using external preparation dosage forms to treat cervical cancer and vulvar cancer , skin cancer, lip cancer and cervical erosion, vulvitis, skin eczema, stubborn ringworm, rheumatic pain and other diseases

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Get 10 grams of elemene that meets China's "National Drug Standard ws-048(x-040)-96" and dissolve it with 1 gram of organic solvent ether, and set aside; take 10 grams of hyaluronic acid, 79 grams of medicinal base petroleum jelly are heated and sterilized (moisture has also been removed), filtered, and set aside. The elemene dissolved in an organic solvent, the sterilized and refrigerated medicinal base, and hyaluronic acid are added to the batching tank, and after mixing evenly, filling, packaging, finished product inspection, and storage are carried out.

Embodiment 2

[0033] The raw and auxiliary materials used are the same as in Example 1, and 50 grams of elemene are weighed and dissolved in 1 gram of organic solvent ethanol for subsequent use; 10 grams of hyaluronic acid and 39 grams of medicinal base petroleum jelly are weighed in a suitable container , heated to 150° C. / 1 hour for sterilization (while also removing water), filtered, and set aside. The elemene dissolved in an organic solvent, the sterilized and refrigerated medicinal base, and hyaluronic acid are added to the batching tank, and after mixing evenly, filling, packaging, finished product inspection, and storage are carried out.

Embodiment 3

[0035] The raw and auxiliary materials used are the same as in Example 1, and 90 grams of elemene are weighed and dissolved in 1 gram of organic solvent acetone for subsequent use; 5 grams of hyaluronic acid and 1 gram of medicinal matrix lanolin are weighed with suitable containers. grams, heated to 150°C / 1 hour for sterilization (while also removing water), filtered, and set aside. The elemene dissolved in an organic solvent, the sterilized and refrigerated medicinal base, and hyaluronic acid are added to the batching tank, and after mixing evenly, filling, packaging, finished product inspection, and storage are carried out.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

An exterior-applied elemene medicine with slow release and low irritation is proportionally prepared from elemene, organic solvent, medicinal matrix, and the additive chosen from hyaluronic acid, sodium hyaluronate gel, hyaluronidase, carbomer, and chitin. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention relates to a preparation of elemene and a preparation method thereof. The preparation can be used to make various external preparations and has antiviral and anticancer effects. Background technique: [0002] Elemene is an active ingredient extracted from Curcuma phaeocalis Valeton. or Curcumakwangsiensis S.G.Lee et C.F. in Guangxi or Curcuma Wenyujin Y.H.chen et C.Ling or other plants in Zingiberaceae. Its English name is Elemene, and its chemical name is 1 -Methyl-1-vinyl-2,4 diisopropenylcyclohexane, molecular formula: C 15 h 24 . Elemene contains a variety of isomers, mainly α-elemene, β-elemene, γ-elemene, δ-elemene, curcumene, and caryrone. The methods for extracting and refining elemene from the above-mentioned plants or from zedoary oil have been reported in many literatures, as described in Chinese patent CN1060038 and Chinese patent CN1200266. Elemene has antiviral and anticancer effects, and the milk injection made of elem...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/36A61K47/42A61K31/015A61P31/12A61P35/00A61K47/44
Inventor 谢瑞钢
Owner 谢瑞钢
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products