50results about How to "Expand the scope of indications" patented technology

The invention relates to a preparation method of tooth color imitating dental tetragonal polycrystalline zirconia ceramics, which specifically comprises the following steps: taking a 3Y-TZP ceramic ingot as the raw material, taking rare earth oxide and transition element oxide as the colorant, adding the colorant and absolute ethyl alcohol into 3Y-TZP, ball milling, adding the 3Y-TZP, the absolute ethyl alcohol and agate ball milling beads into an agate ball milling pot by the mass ratio of 1:1:1, then drying, dry pressing and forming, isopressing and forming; and sintering at normal pressure, cutting and forming to obtain the tooth color imitating dental tetragonal polycrystalline zirconia ceramics. The preparation method of tooth color imitating dental tetragonal polycrystalline zirconia ceramics has the advantages that the chromatic values of 6 types of zirconia ceramics are within the range of natural tooth color, the color stability is good, the mechanical properties are excellent, and a constructed two-stage sintering process is beneficial to industrialized popularization, expands the adaptation disease scope thereof in dental clinical medicine and provides bases for the localization thereof.

The invention provides a novel oral cavity orthodontic appliance, wherein the appliance comprises a tooth socket body, and a orthodontic bench is arranged on the tooth socket. The orthodontic bench is arranged on a lingual side of incisors or a lingual sides of incisors and canine teeth of the tooth socket body, and comprises a contact surface and a holding surface, wherein one end of the contact surface is connected with the tooth socket body, the other end of the contact surface is connected with the holding surface, and the orthodontic bench is a plat bench or a sloping bench, when the orthodontic bench is a plat bench, the contact surface matches with a occlusalf surface of maxillary-mandibular teeth, when the orthodontic bench is a sloping bench, the contact surface is in parallel with a lingual side of the a occlusalf surface of maxillary-mandibular teeth, or the contact surface and the a occlusalf surface of maxillary-mandibular teeth form an included angle. According to the invention, an ordinary tooth socket and a flat bite plate or an inclined bite plate are integrated into one body to replace the clasp and the flat bite plate or the inclined bite plate with adjacent hook-type retention. The appliance provided in the invention enlarges indication scope of orthodontic invisable aligner technique, and the appliance can be applied in a bracket treatment system. The appliance has characteristics of comfortable wear, transparentness and beautiful look, and is made of an elastic polymer material. The appliance can give continuous elastic force to the tooth that needs to be intruded or led, so that the orthodontic effect is better.

The invention belongs to the technical field of cross of medicine and engineering and relates to an in-situ laser pulse artery opening device and application thereof. The in-situ laser pulse artery opening device comprises aorta covered stents including the Valiant stent, the zenith flex stent, the Ankura chest aorta covered stent and the chimney stent and a laser. According to the in-situ laser pulse artery opening device, after the aorta covered stents are released, according to the blood vessel condition, the aorta covered stents corresponding to branch blood vessels can be opened through the laser, and the covered stents or bare stents are planted into the opened branch blood vessels to rebuild blood flows of the branch blood vessels and reduce occurrence of relevant complications. According to the in-situ laser pulse artery opening device, the covered stents of standard specifications are adopted, no anatomical structure is destroyed, a stent system does not need to be customized independently according to the individual special anatomical form, and the in-situ laser pulse artery opening device can be used for treating aortic aneurysm or aortic dissection diseases.

The invention relates to ganoderma lucidum tea and a preparation method thereof, belonging to the field of health-care products. The ganoderma lucidum tea is of granulated shape and comprises the components of ganoderma capense, ganoderma sinense, ganoderma lucidum Karst and raw ganoderma spore powder in the mass ratio of (5-20):(3-10):(2-10):1. Since the ganoderma capense, the ganoderma sinense,the ganoderma lucidum Karst and the ganoderma spore powder of the ganoderma sinense and the ganoderma lucidum Karst are selected as raw materials, the defects of uneven active component contents of asingle ganoderma lucidum raw material or much low active component contents of a part of raw materials are overcome, the complementary advantages of efficacies of different ganoderma lucidums are given to full play and the indication range of the ganoderma lucidum tea is expanded. The ganoderma lucidum tea is prepared with a special process by utilizing pure lucid ganoderma as the raw material without adding any auxiliary material, wherein a pharmaceutic adjuvant is replaced with the sporoderm-unbroken raw ganoderma spore powder as a pelletizing adhesive, and originally nonviscous ganoderma lucidum stipe and pileus as raw materials are prepared into ganoderma lucidum pulvis which is convenient for packaging, storage and brewing.

Because of poor solubility in water, Ulifloxacin has low bioavailability. The invention relates to a novel Ulifloxacin mesylate, a preparation thereof, a kit comprising the medical antibiotic preparation, and application of the novel Ulifloxacin mesylate in preparing an anti-infective medicament. The invention specifically relates to a novel medicinal preparation which is used for injection and remains stable in storage; the chemical name of the preparation is 6-fluorine-1-methyl-7-(1-piperazinyl)-4-oxo-4H-[1,3]thiadiazolebutane[3,2-a]quinoline-3-mesylate. In the invention, injection and administration are carried out directly in the form of Ulifloxacin mesylate, and therefore solubility and bioavailability of Ulifloxacin are enhanced, and treatment effects of the preparation are improved simultaneously.

The invention discloses an optical-medical heat moxibustion treatment device. The optical-medical heat moxibustion treatment device comprises a modern moxibustion controller and a moxibustion treatment head, wherein internal elements are packaged inside the moxibustion treatment head; the internal elements comprise a heating element, a temperature measuring head, light emitting diodes and current-limiting resistors of the light emitting diodes; radiation heads of the light emitting diodes are distributed, mounted and exposed on the periphery of the heating working surface of the moxibustion treatment head; a dedicated medical juice containing gauze application plane is arranged in the center of the heating working surface. The heating working surface of the moxibustion treatment head coated with the medical juice containing gauze is tightly fit to acupuncture points of a human body, a power supply of the modern moxibustion controller is turned on, and then the generated circle of red light on the periphery of the heating working surface (2) of the moxibustion treatment head covers the acupuncture points and injects in red optical energy; furthermore, the acupuncture points are stimulated by the medicine generated by the large amount of medical juice in the center, and the heat moxibustion is utilized to synergistically treat the human body, so that the optical-medical heat moxibustion treatment device can achieve ideal optical, medical and heat moxibustion treatment effects.

The invention discloses application of emricasan in the preparation of a medicine for treating ischemia/reperfusion injury. By using emricasan in treatment of ischemia/reperfusion injury, especially treatment of brain tissue neuropathy and even especially protective effect of cerebral ischemia/reperfusion (cerebral arterial thrombosis), cerebral ischemia/reperfusion injury can be remarkably mitigated.

The invention discloses a drawstring assembly tool for a magnetic stapler, comprising a magnetic stapler and an assembly mechanism thereof. The magnetic stapler includes a first body and a second body oppositely arranged, and the first body and the second body are provided with The magnets attract each other, the first body and the second body are provided with a communicating through hole, the assembly mechanism passes through the through hole, the assembly mechanism includes an operating rod that is engaged with the second body, and the operating rod is provided with a The top block of the two bodies and the pull cord that pulls the second body, the pull cord has a first state of tightening the connection between the operating rod and the second body and a second state of loosening the operating rod to separate from the second body. The advantage is that the circular stapler in the nail anastomosis and the magnetic stapler in the magnetic anastomosis are combined, and the connection and separation of the circular stapler and the magnetic stapler can be realized through the top block and the drawstring, and the comprehensive It has the advantages of magnetic anastomosis and nail anastomosis, and avoids the disadvantage of nail anastomosis that easily leads to anastomotic stenosis.

The invention belongs to the field of health-care products, and in particular relates to a ganoderma liver-protection tea and a preparation method thereof. The preparation method of the ganoderma liver-protection tea comprises the steps of: crushing, mixing, stirring, pelletizing and drying ganoderma capense, ganoderma sinense, ganoderma lucidum karst and raw ganoderma lucidum spore powder to obtain pure ganoderma tea particles, and then spraying traditional Chinese medicine extract on the surface of the pure ganoderma tea particles for drying, thus obtaining the ganoderma liver-protection tea. The ganoderma liver-protection tea adds various traditional Chinese medicinal materials for tonifying and nourishing the liver into raw ganoderma, thus having the obvious effect of protecting the liver; when being supplied for patients with different types of hepatopathy for long-term drinking, the ganoderma liver-protection tea can be cooperative with the conventional hepatopathy drugs so as to protect the liver, degrade enzyme, prevent and treat diseases, and has an obvious curative effect especially on chronic hepatitis, chronic active hepatitis earlier-cirrhosis. The ganoderma liver-protection tea has no toxic and side effects, can be conveniently administrated, and is suitable for long-term administration by patients.

The invention provides a liquid fermentation method of ginseng-radix astragali-lucid ganoderma medical mycoplasm, and belongs to the field of traditional Chinese medicine biological fermentation. According to the liquid fermentation method of ginseng-radix astragali-lucid ganoderma medical mycoplasm, a liquid fermentation culture medium is inoculated with lucid ganoderma strains preserved in PDA culture medium, wherein the liquid fermentation culture medium is made from ginseng and radix astragali water extracts; culturing is carried out at a temperature of 22 to 30 DEG C with a rotating speed of 100 to 180r/min for 10 to 20 days so as to obtain the ginseng-radix astragali-lucid ganoderma medical mycoplasm. The liquid fermentation culture medium is made from ginseng and radix astragali water extracts, no other chemical ingredient is added, so that the liquid fermentation culture medium is safe and harmless; ginseng and radix astragali are combined, so that drug property and effect deficiencies of ginseng and radix astragali are avoided, and application range is widened; and in addition, the obtained ginseng-radix astragali-lucid ganoderma medical mycoplasm contains active ingredients of ginseng, radix astragali, and lucid ganoderma because of lucid ganoderma fermentation, effective combination of the three traditional traditional Chinese medicine ingredients is realized, balance of drug property and effect is achieved, and biological activities of original medicinal materials are improved.

The invention discloses a traditional Chinese medicine health-preserving wine, wherein the raw materials are grain and a traditional Chinese medicine composition, and the mass ratio of the grain to the traditional Chinese medicine composition is 2: 5 to 1: 2; The grain is one or more of rice, glutinous rice or corn; A Chinese medicinal composition comprise radix Angelicae sinensis, radix ginseng,fructus Lycii, radix astragali, radix rehmanniae and flos Chrysanthemi; The invention adopts the Chinese herbal medicines for both medicinal and edible purposes as the formula, and combines the modernscientific and technological biological fermentation technology to prepare the Chinese herbal health wine, solves the taste problem of the health wine, and breaks through the bottleneck of the poor taste of the traditional health wine.

The invention discloses application of ponatinib in the preparation of a medicine for treating ischemia/reperfusion injury. By using ponatinib in treating ischemia/reperfusion injury, especially in treating brain tissue neuropathy and even especially in the protective effect on ischemic cerebral apoplexy, cerebral ischemia/reperfusion injury can be remarkably mitigated.

An exterior-applied elemene medicine with slow release and low irritation is proportionally prepared from elemene, organic solvent, medicinal matrix, and the additive chosen from hyaluronic acid, sodium hyaluronate gel, hyaluronidase, carbomer, and chitin. Its preparing process is also disclosed.

The conveying device comprises an outer sheath tube, a multi-cavity tube and an inner catheter, the multi-cavity tube is provided with a fixing cavity and a guiding cavity which are axially through, the multi-cavity tube comprises a main body section and a reducing section located at the far end of the main body section, and the diameter of the reducing section is smaller than that of the main body section; a containing gap is formed between the outer wall of the reducing section and the inner wall of the outer sheath tube, the inner catheter is connected into the fixing cavity in a sleeved mode and is relatively fixed to the multi-cavity tube, the far end of the inner catheter extends out of the far end of the multi-cavity tube, and the multi-cavity tube and the inner catheter are movably arranged in an inner cavity of the outer sheath tube in the axial direction of the outer sheath tube at the same time. According to the conveying device and the stent system, the inflection section formed when the branch sheath controls the guide wire to be inflected is contained in the containing gap, under the condition that the diameter of the multi-cavity tube is not reduced, the maximum diameter of the outer sheath tube can be effectively reduced, wounds are reduced, the conveying device and the stent system are suitable for more patients, and the indication range is expanded; and a doctor is more convenient to use and simpler to operate during an operation.

The invention relates to the technical field of traditional Chinese medicines, and discloses dracocephalum tanguticum Tibetan decoction pieces and a processing method thereof. The dracocephalum tanguticum Tibetan decoction pieces are prepared from decoctions of radix scutellariae, radix bupleuri, rhizoma coptidis, semen plantaginis and radix inulae racemosae through wetting and stir-frying. The decoction pieces are formed by processing the decoctions of radix scutellariae, radix bupleuri, rhizoma coptidis, semen plantaginis and radix inulae racemosae by following the ancient traditional processing technology and combining the compatibility theory of traditional Chinese medicines, the effects of clearing the liver, removing dampness and regulating qi and the stomach are added on the basis of the original effect of liver-stomach heat clearing of dracocephalum tanguticum, the prepared dracocephalum tanguticum decoction pieces have significantly increased total flavonoids and oleanolic acid, the overall effect is superior to that of the traditional processing technology, and side effects are obviously reduced.

The invention relates to application of oxalomalic acid in the preparation of drugs to treat nerve cell injury. When applied to the treatment of ischemia reperfusion injury, in particular to the treatment of brain tissue neuropathy, more in particular to the protection of ischemic stroke, the oxalomalic acid can evidently relieve cerebral ischemia/reperfusion injury, alleviate cranial nerve cell injury, and improve nerve cell functionality.

The invention discloses compound amoxicillin powder and a preparation method thereof. The compound amoxicillin powder is prepared from the following components in parts by mass: 4-20 parts of amoxicillin, 1-2 parts of clavulanic acid, 0.2-1.5 parts of antioxidant, 0.5-2.5 parts of moisture absorption resistant auxiliaries, 1-2 parts of methanol, 0.5-1.5 parts of ethanol, 2-2.5 parts of sodium chloride, 1-3 parts of ethyl acetate, 1.5-5 parts of fructus forsythia extract, 3-6 parts of aerosil and 1.2-2.5 parts of phosphate buffer. The preparation method comprises the following steps: sequentially adding the water, sodium chloride, ethanol and methanol into the fructus forsythia extract and antioxidant to obtain a mixed solution; weighing amoxicillin and clavulanic acid, adding into the mixed solution; and adding the moisture absorption resistant auxiliaries, ethyl acetate, phosphate buffer and aerosol to obtain the compound amoxicillin powder. According to the compound amoxicillin powder, the curative effect is reinforced, the problem of bacterial drug resistance can be solved, toxic and side effects can be reduced, the indication range is enlarged, the course of treatment can be shortened, the dosage can be reduced, and medicinal materials can be saved.