Production of complex carbohydrates

US20060099691A1Inactive Publication Date: 2006-05-11UNIV OF IOWA RES FOUND +1
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
UNIV OF IOWA RES FOUND
Publication Date
2006-05-11
Estimated Expiration
Not applicable · inactive patent

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Abstract

Compositions and methods for making complex carbohydrates in a bacterial production cell are disclosed. The complex carbohydrates that can be made include oligosaccharides and polysaccharides of bacterial or mammalian origin.
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Description

CLAIM OF PRIORITY

[0001] This application claims priority under 35 U.S.C. 119(e) from U.S. Provisional Application Ser. No. 60 / 134,756, filed May 18, 1999, which application is incorporated herein by reference.GOVERNMENTAL RIGHTS

[0002] The United States Government retains certain rights in this invention. Financial support was provided by the National Institute of Allergy and Infectious Diseases under Grant Number A124016 and from the NIH National Center for Research Resources under Grants Number RR01614 and RR04112.FIELD OF THE INVENTION

[0003] This invention relates to a method for the production of complex carbohydrates on an LPS backbone structure in Gram-negative bacteria BACKGROUND OF THE INVENTION

[0004] Complex carbohydrates occur in nature and are involved in a wide array of biological functions, including viral, bacterial and fungal pathogenesis, cell-to-cell and intracellular recognition, binding of hormones and pathogens to cell-surface receptors and in antigen-antibody...

Claims

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