Minimally invasive collection probe and methods for the use thereof

a collection probe and minimally invasive technology, applied in the field of medicine, molecular biology and biochemistry, can solve the problems of difficult recognition of certain tumor cells, unreliable and subjective analysis, and many challenges, and achieve the effect of easy identification, easy reading and removal
US20200305723A1Inactive Publication Date: 2020-10-01BOARD OF RGT THE UNIV OF TEXAS SYST
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Patent Information

Authority / Receiving Office
US · United States
Current Assignee / Owner
BOARD OF RGT THE UNIV OF TEXAS SYST
Publication Date
2020-10-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for minimally invasive collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis.
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Description

[0001] This application is a continuation of International Application No. PCT / US2018 / 062625 filed Nov. 27, 2018, which claims the benefit of U.S. Provisional Patent Application No. 62 / 591,179, filed Nov. 27, 2017 and 62 / 640,385, filed Mar. 8, 2018, each of which are incorporated herein by reference in their entirety.

[0002] This invention was made with government support under Grant No. R00 CA190783 awarded by the National Institutes of Health. The government has certain rights in the invention.BACKGROUND OF THE INVENTION1. Field of the Invention

[0003] The present invention relates generally to the field of medicine, molecular biology and biochemistry. More particularly, it concerns methods and devices for assessment of tissue samples using mass spectrometry.2. Description of Related Art

[0004] Clinical diagnosis is commonly performed through the evaluation of tissue samples pre-operatively, intra-operative, and post-operatively, at several other stages of the patient's treatment process...

Claims

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