The invention discloses an innovative method for management of scientific and technological resources. By analyzing the attributes, characteristics and current situation of scientific and technological resources, it adopts the principles of "data life cycle theory", "requirement hierarchy theory of scientific and technological resources" and "big data processing" for scientific and technological resources. Three research methods, put forward the overall structure of scientific and technological resources innovation management, realize the integration, optimization and sharing of scientific and technological resources, standard system construction, quality management, ecological chain management, performance management and other innovative measures and methods, in order to achieve the maximum utilization rate of scientific and technological resources change. The data life cycle theory includes the generation period, integration optimization period, storage period, service period and decline period; the science and technology resource demand hierarchy theory divides the use demand of science and technology resources into acquisition demand, possession demand, interaction demand and quality demand and sharing requirements; the big data processing divides scientific and technological resources into data layer, processing layer and application layer, in order to achieve hierarchical, integrated and intensified data resources.