The invention discloses a cloud manufacturing service system based on the product life cycle. The cloud manufacturing service system comprises a business negotiation module, a collaborative design and development design module, a sample piece trial-manufacturing module, a checkout detection module, a bulk ordering module, a material purchasing module, a production management module, a sale management module and an after-sales service module. By means of the cloud manufacturing service system, the efficiency and the quality in the product life cycle including research and development design, material purchasing, product production, selling and the like are better improved, management in the product life cycle including product research and development design, material purchasing, product production, selling and the like is specified, the product research and development period is shortened, the operating cost of an enterprise is reduced, improving of the product innovation capability in the manufacturing industry is promoted, the market competitiveness of the manufacturing enterprise is strengthened, and the rapid development of the manufacturing industry in China is pushed.