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Chinese medicine composition for treating baldness and its preparing method

The technology of a composition and traditional Chinese medicine is applied in the field of medicines for treating hair loss, and can solve the problems such as the inability of the dosage form to meet the needs of patients, the loss of volatile oil components, and the long disintegration time of the pills.

Inactive Publication Date: 2007-08-29
广州花海药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the original dosage form is water honeyed pill or big honeyed pill, which cannot meet the needs of patients
The disintegration time of the pills is long and the medicinal materials have not been extracted, resulting in low bioavailability of the preparation, and the volatile oil components in the medicinal materials are also easily lost during storage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The preparation of embodiment 1 Chinese medicine composition capsule of the present invention

[0021] a) Weigh 242g of rehmannia glutinosa, 242g of rehmannia glutinosa, 242g of Radix Polygoni Multiflori, 160g of Salvia miltiorrhiza, 160g of fried peony root, 82g of papaya, 160g of angelica, 160g of schisandra and 82g of notopterygium by weight, and set aside;

[0022] b) extract the volatile oil from angelica, schisandra, and notopterygium by steam distillation, separate and filter to obtain volatile oil 1 and filtrate 2, add 8 times the amount of water to the dregs, decoct for 1 hour, filter to obtain filtrate 3, and set aside;

[0023] c) Boil rehmannia glutinosa, rehmannia glutinosa, Radix Polygoni Multiflori, Salvia miltiorrhiza, fried white peony root, and papaya twice, add 9 times the amount of water for 1.5 hours for the first time, add 7 times the amount of water for 1 hour for the second time, The decoction was combined and filtered to obtain filtrate 4, which...

Embodiment 2

[0027] The preparation of embodiment 2 Chinese medicine composition tablet of the present invention

[0028] It is basically the same as Example 1, the difference is that in step f) take the dry extract 5 and add an appropriate amount of auxiliary materials, make granules and then dry, add volatile oil clathrate 6 and appropriate amount of auxiliary materials, mix evenly, and press into 1000 tablets.

[0029] Usage and dosage of the above-mentioned capsules or tablets: take orally, 3 capsules (tablets) each time, 3 times a day.

experiment example 1

[0030] Experimental example 1 drug efficacy experiment

[0031] Chinese medicine composition experimental result of the present invention is as follows:

[0032] 1. The large and medium dosage groups of the Chinese medicine composition of the present invention have obvious promoting effect on the prepuce gland; the effect on the seminal vesicle and the prostate is more significant; but the effect on the levator ani muscle is not obvious; the Chinese medicine composition of the present invention has obvious kidney-tonifying effect effect.

[0033] 2. To the mouse hemorrhagic anemia model, 3 dosage groups of the Chinese medicine composition of the present invention all have the effect of obviously increasing red blood cell quantity and hemoglobin content; To the model of cyclophosphamide aplastic anemia, 3 Chinese medicine compositions of the present invention All doses have the effect of significantly increasing the red blood cells and white blood cells of mice, but the effect...

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PUM

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Abstract

The Chinese medicine composition for treating baldness is prepared with rehmannia root, prepared rhizome of rehmannia, prepared fleeceflower root, red sage, white peony root, papaya, angelica, schisandra and notopterygium. The preparation process includes weighing material; distilling angelica, schisandra and notopterygium to extract volatile oil and obtain water solution via filtering; decocting the other materials including the distilled residue, filtering, concentrating to obtain extractum; including the volatile oil with beta-cyclodextrin and drying to obtain inclusion; mixing the extractum, the inclusion and supplementary material; and tabletting or encapsulating. The Chinese medicine composition has the advantages of high bioavailability, high medicinal effect, small dosage and convenient carrying about.

Description

technical field [0001] The invention relates to a medicine for treating alopecia, in particular to a traditional Chinese medicine composition for treating hair loss, and also relates to a preparation method of the Chinese medicine composition. Background technique [0002] Alopecia areata is a relatively common disease in dermatology. According to clinical findings, due to the accelerated pace of life, increased work pressure, and aggravated environmental pollution, the immune system function of the human body has been affected, and the number of patients suffering from hair loss has increased. According to clinical findings and related literature reports, this disease has an increasing trend. The domestic survey results of 1766 Han males show that there are 533 male pattern baldness patients, and the prevalence rate reaches 30.2%. Higher, such as 71% in Japan. In addition, with the increasing incidence of tumors and cancers, the use of radiotherapy and chemotherapy is also...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/804A61K36/732A61K36/71A61K36/704A61K36/57A61K36/53A61K36/237A61K36/232A61K9/20A61K9/48A61P17/14
Inventor 吴智南黄能章招翠微
Owner 广州花海药业股份有限公司