Quaternary bis-ammonium salt diamine fluoride and preparation method thereof

A double quaternary ammonium salt, fluorination technology, applied in chemical instruments and methods, botanical equipment and methods, preparation of organic compounds, etc., can solve the problem of poor Gram-negative bacteria effect, increased material water absorption, monoquaternary The problem of large amount of salt, etc., to achieve the effect of easy source of raw materials, good bactericidal effect, and easy control of the reaction process
CN100376550CInactive Publication Date: 2008-03-26SICHUAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SICHUAN UNIV
Publication Date
2008-03-26
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention discloses fluoric double quaternary ammonium salt diamine in the structure as shown and its preparation process. The fluoric double quaternary ammonium salt diamine has two primary amino radicals with excellent reaction activity in its structure, so that it may be introduced into polymer easily to form polymer with excellent effect of killing Gram negative bacteria. The preparation process adopts facile industrial materials and includes serial simple easy-to-control chemical reactions.
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Description

technical field

[0001] The invention belongs to the technical field of bisquaternary ammonium salt and its preparation, and in particular relates to a fluorinated bisquaternary ammonium salt diamine and a preparation method thereof. Background technique

[0002] Since Heidelberger (Jacobs WA, Heidelberger M. The quaternary salts of hexamethylene eteramine I. Substituted benzyl halides and the hexamethylene etrammonium salts derived therefrom. J. Biol Chem. 1915; 20: 659-83; Jacobs WA, Heidelberger of M. The bacteria of quaternary prots Hexamethyleneetramine I.the problem of the chemotherapy of experimental bacterial infections.J Exp Med, 1916; 23:563-8) reported in 1915 that quaternary ammonium salts had broad-spectrum bactericidal functions, water-soluble quaternary ammonium salts were used as bactericides in various It has been widely used in the industry. Although quaternary ammonium salts (QAS) have been widely used, studies have also found that some bacteria, especiall...

Claims

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