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Capsule for treating enteritis and dysentery and its preparing process

A technology for dysentery and enteritis is applied in the field of capsules for treating enteritis and dysentery and its preparation technology, which can solve the problems of life-threatening, large side effects and the like, and achieve the effects of being convenient to carry, good in stability and high in bioavailability

Active Publication Date: 2009-05-06
江西聚仁堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And at home and abroad the western medicine that treats diseases such as enteritis dysentery, furunculosis traumatic inflammation, mastitis, cholecystitis is quite big to the side effect of human body, even life-threatening, can not be used more.

Method used

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  • Capsule for treating enteritis and dysentery and its preparing process
  • Capsule for treating enteritis and dysentery and its preparing process
  • Capsule for treating enteritis and dysentery and its preparing process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Berberine Hydrochloride 10g Dandelion Extract 187.5g

[0013] The preparation method of the present invention: take berberine hydrochloride and dandelion extract, add 52.5 g of starch and mix thoroughly, make granules with 75% ethanol, dry, fill into 1000 capsules, and get final product.

[0014] Preparation method of dandelion extract: Take dandelion medicinal material, grind it into fine powder, pass through a 100-mesh sieve, and set aside; take another dandelion medicinal material and add 12 times the amount of water to decoct twice, the first time is 1.5 hours, the second time is 1 hour, combined decoction Liquid, filtered, the filtrate concentrated to a clear paste with a relative density of 1.20, measured at a temperature of 70-75°C, take 1.2 parts of the clear paste, 1 part of dandelion fine powder, mix well, dry, and make a dry paste.

Embodiment 2

[0016] Berberine Hydrochloride 7g Dandelion Extract 127.5g

[0017] The preparation method of the present invention: take berberine hydrochloride and dandelion extract, add 52.5 g of starch and mix thoroughly, make granules with 65% ethanol, dry, fill into 1000 capsules, and get final product.

[0018] Preparation method of dandelion extract: Take dandelion medicinal material, grind it into fine powder, pass through a 100-mesh sieve, and set aside; take another dandelion medicinal material and add 12 times the amount of water to decoct twice, the first time is 1.5 hours, the second time is 1 hour, combined decoction Liquid, filtered, the filtrate concentrated to a clear paste with a relative density of 1.20, measured at a temperature of 70-75°C, take 1.2 parts of the clear paste, 1 part of dandelion fine powder, mix well, dry, and make a dry paste.

Embodiment 3

[0020] Berberine Hydrochloride 13g Dandelion Extract 247.5g

[0021] The preparation method of the present invention: take berberine hydrochloride and dandelion extract, add 52.5 g of starch and mix thoroughly, make granules with 85% ethanol, dry, fill into 1000 capsules, and obtain.

[0022] Research result:

[0023] 1. Preparation process research data

[0024] 1 Discussion on the efficacy and ingredients related to process selection

[0025] This prescription is composed of berberine hydrochloride and dandelion extract.

[0026] 1.1. Berberine hydrochloride is the raw material drug, which has strong antimicrobial and antiprotozoal effects; berberine hydrochloride has the effects of lowering blood pressure, relaxing vascular smooth muscle, promoting choleresis, antidiuresis, local anesthesia, sedation, and analgesia. Therefore, in order to retain its active ingredients to the greatest extent, it is more reasonable to adopt the direct addition process of berberine hydrochl...

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PUM

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Abstract

The capsule for treating enteritis and dysentery contains main medicine components berberine hydrochloride and taraxacum extract and supplementary material starch. The medicine of the present invention has masked bitter, high bioavailability, high medicine stability, and carrying and use convenience. The preparation process includes mixing berberine hydrochloride, taraxacum extract and starch, adding 75 % concentration ethanol solution, pelletizing, drying, and encapsulating.

Description

technical field [0001] The invention relates to a capsule for treating enteritis and dysentery and a preparation process thereof. Background technique [0002] Lianpu Shuangqing Tablet, which is made of berberine hydrochloride and dandelion extract as the main raw materials, has a relatively good curative effect on the treatment of enteritis and dysentery, boils, traumatic inflammation, mastitis, and cholecystitis. It is very important to re-develop the Chinese patent medicine Lianpu Shuangqing Capsule, because changing it into a capsule has many advantages: it can mask the bitter taste of the medicine, it can have various colors and can be printed, and it is beautiful, easy to take, easy to carry and use, and the bioavailability of the medicine High degree, improve drug stability. [0003] At present, there are relatively many Chinese patent medicines in China for the targeted treatment of enteritis and dysentery, boils, traumatic inflammation, mastitis, and cholecystitis....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/288A61K31/437A61K9/48A61P1/00A61P1/12
CPCY02A50/30
Inventor 胡乐平夏颖
Owner 江西聚仁堂药业有限公司