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Stomach harmonizing liver calming fast dispersion solid preparation and its preparation method

A solid preparation and rapid technology, which can be used in medical preparations containing active ingredients, pill delivery, pharmaceutical formulations, etc., can solve problems such as inconvenience in use and outdated preparation technology, and achieve increased dispersion, convenient administration, and improved bioavailability. Effect

Inactive Publication Date: 2009-07-22
JIANGXI HUIREN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Hewei Pinggan Pills have already been sold in the domestic market, but in practice, the disadvantages of Hewei Pinggan Pills are that the preparation process is outdated, and the dosage form is honeyed pills, which is inconvenient to use and brings pain to the elderly, young and patients with dysphagia. a lot of trouble

Method used

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  • Stomach harmonizing liver calming fast dispersion solid preparation and its preparation method
  • Stomach harmonizing liver calming fast dispersion solid preparation and its preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0041] 309g of agarwood, 150g of bergamot, 240g of woody incense, 30g of sandalwood, 240g of amomum, 180g of cardamom, 300g of citrus aurantium (stir-fried with bran), 180g of Magnolia officinalis (steamed with ginger), 450g of Toosendan, 300g of corydalis (steamed with vinegar), 240g tangerine peel, 300g sliced ​​turmeric, 360g white peony root, 300g poria cocos, and the above fourteen flavors, after preliminary crushing, carry out ultrafine grinding, and pass through 400 meshes; every 100 parts of powder and auxiliary materials are mixed evenly, and the powder is pressed into large tablets (2g). Fil coating material coating, that is. This product is a dispersible tablet, orally, 1 tablet at a time; or put into about 150-200ml of water to disintegrate into a uniform solution and take it; 2 times a day. The formulation prescription is shown in Table 1:

[0042] Table 1 Preparation prescription and its main evaluation results

[0043]

[0044] Note: (1) The amount of the m...

Embodiment 2

[0046] 240g of rhubarb, 200g of morning glory (stir-fried), 80g of gardenia (steamed with ginger), 120g of gypsum, 80g of Glauber’s salt, 80g of skullcap, 20g of berberine, 80g of forsythia, 160g of hawthorn (stir-fried), 160g of tangerine peel, 80g of magnolia (steamed with ginger) , Citrus aurantium 80g, Rhizoma Cyperi 40g, Pig tooth soap 120g, Nepeta panicle 40g, Mint 40g, Fangfeng 40g, Chrysanthemum 40g, Angelica dahurica 120g, Campanulaceae 80g, Scrophulariaceae 120g, Licorice 40g, Bezoar 13g, Borneol 51.5g, the above twenty Four flavors, bezoar, and borneol are ground into fine powder, and the rest are decocted with 8 times the amount of water to extract for 2 hours, filtered, and then added with 6 times of water, decocted and extracted for 2 hours, filtered; the water is combined twice, and the filtrate is concentrated to a relative density It is a thick paste of 1.30~1.35 (60°C), dried, crushed into fine powder, sieved, ultrafinely pulverized, and passed through 400 mes...

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Abstract

The invention relates to a fast-dispersing solid preparation for harmonizing the liver and calming the liver, which is prepared from the following traditional Chinese medicine raw materials in the weight ratio: 309 parts of agarwood, 150 parts of bergamot, 240 parts of woody incense, 30 parts of sandalwood, 240 parts of amomum, and cardamom 180 parts, Citrus aurantii (stir-fried with bran) 300 parts, Magnolia officinalis (Ginger roast) 180 parts, Toosendan 450 parts, Corydalis Corydalis (vinegar roasted) 300 parts, Chenpi 240 parts, Turmeric slices 300 parts, Paeoniae Alba 360 parts, Poria cocos 300 parts, it is characterized in that, the described fast dispersing solid preparation is after pulverizing or extracting the above-mentioned traditional Chinese medicine, and carries out superfine pulverization, obtains main ingredient, and this main ingredient is selected from disintegrating agent, binder, suspending agent, flow aid The auxiliary materials of the agent, flavoring agent and color correcting agent are mixed, and the preparation is made by the conventional technology of pharmacy, wherein the particle size of all the main ingredients and auxiliary materials used is less than 75 μm.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a fast-dispersing solid preparation with traditional Chinese medicine Hewei Pinggan and a preparation method thereof. technical background [0002] Hewei Pinggan Pill is a commonly used traditional Chinese patent medicine recorded in the "Standards of Chinese Patent Medicine of the Ministry of Health". Sunburn), Toosendan, Corydalis Corydalis (roasted with vinegar), tangerine peel, sliced ​​turmeric, white peony root, Poria cocos and other fourteen flavors, which have the effect of soothing Qi, calming the liver, harmonizing the stomach and relieving pain, and are used for liver and stomach disharmony and stagnation of Qi Two hypochondriacs are distended, fullness is noisy, qi is reversed and nauseated, epigastric pain is tingling, food and drink are tasteless. Currently in the "Ministry of Health Standards of Chinese Patent Medicine" (6 volumes, standard number WS3-...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/9066A61K36/9064A61K36/835A61K36/752A61K36/75A61K36/71A61K36/66A61K36/58A61K36/575A61K36/285A61K36/185A61K36/076A61P1/14A61P1/16
Inventor 宋浩亮杨明耿炤蔡金娜梅玲华
Owner JIANGXI HUIREN PHARMA CO LTD
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