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Cinnamon poria capsule and its preparation process

A technology of cassia tuckahoe and soft capsules is applied in the directions of capsule delivery, medical preparations containing active ingredients, plant raw materials, etc., which can solve the problems of easy-to-grow bacteria and mildew, difficulty in storage, slow dissolution, etc., and reduce the cost of raw materials. , to ensure full utilization, the effect of fast absorption in the body

Inactive Publication Date: 2010-02-03
江西欧氏药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are only two dosage forms of this product: water pill and dense pill, both of which belong to pills, and after taking pills, they dissolve slowly in the gastrointestinal tract, and the dosage is large. When the production technology is improper, the dissolution time limit is difficult to control, and it is easy to be contaminated by microorganisms. , easy to grow mold
In addition, the preparation of water pills is more complicated, and pan pills have strict requirements on the experience and proficiency of workers, the content of the main drug in the finished product is difficult to control, the amount of dense pills is large, and the disadvantages such as easy moisture absorption and difficult storage are difficult to solve

Method used

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  • Cinnamon poria capsule and its preparation process
  • Cinnamon poria capsule and its preparation process
  • Cinnamon poria capsule and its preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1, the preparation of Guizhi Fuling Soft Capsule

[0040] 1. Preparation of compound active ingredients: Weigh 398.7g of Guizhi, 398.7g of Poria, 398.7g of Radix Paeoniae Rubra, 398.7g of Peach Kernel, and 398.7g of the five medicinal materials three times each, and grind the Guizhi and Poria cocos into fine powder respectively; add 10 times the amount of water to the remaining three flavors Decoct twice, the first time for 3 hours, the second time for 2 hours, combine the decoction, filter, the filtrate is concentrated to a clear paste with a relative density of 1.20 (80°C), spray-dried into a dry paste powder, and the above fine powder Mix to get 2206 grams of compound active ingredients.

[0041] 2. Prepare the contents: take 200 grams of beeswax, 600 grams of coconut oil, and 200 grams of hydrogenated vegetable oil, heat to 80°C to melt, stir well and let cool as suspending agent.

[0042] 2,860 grams of soybean oil, 660 grams of suspending agent, and 80...

Embodiment 2

[0045] Embodiment two, the preparation of Guizhi Fuling Soft Capsule

[0046] 1, preparation compound active ingredient: with embodiment one.

[0047] 2. Prepare the contents: 2200 grams of corn oil, 220 grams of beeswax, and 802.2 grams of spar, heat to 60°C to melt, stir well, and use it as an oil-soluble matrix; then mix with medicinal powder, and stir well.

[0048] 3. Preparation of capsule material: same as in Example 1.

[0049] 4, compressed soft capsule: with embodiment one.

Embodiment 3

[0050] Embodiment three, the preparation of Guizhi Fuling Soft Capsule

[0051] 1, preparation compound active ingredient: with embodiment one.

[0052] 2. Prepare the contents: 3960 grams of peanut oil, 1320 grams of beeswax, and 8023 grams of spar, heated to 60 ° C to melt, stir well, as an oil-soluble matrix; then mix with medicinal powder, stir well.

[0053] 3. Preparation of capsule material: same as in Example 1.

[0054] 4, compressed soft capsule: with embodiment one.

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Abstract

The present invention relates to a ramulus cinnarnomi poria pill and soft capsule with new dosage form and the making method. It is composed of the content and capsule material, the content includes:compound active ingredient, diluent and auxiliary suspending agent, their proportion by weight is: one colon one point zero to one point eight colon zero point one to zero point six colon zero point double zeroes one to zero point zero one. The material of the capsule is basically composed of gelatin, plasticizer and water, the proportion of the three materials by weight is: one colon zero point three to zero point four colon zero point seven to one point four.

Description

technical field [0001] The invention relates to a new dosage form of Guizhi Fuling soft capsules of Guizhi Fuling pills and capsules and a preparation process thereof. Background technique [0002] Guizhi Fuling Pill comes from Zhang Zhongjing's "Synopsis of the Golden Chamber", which is a traditional famous prescription commonly used in clinical Chinese medicine. According to modern clinical reports, this product is not only used for the traditional treatment of dysmenorrhea, irregular menstruation, dysmenorrhea, uterine fibroids, and persistent lochia, but also has a good curative effect on various diseases. Such as ovarian cysts, adnexitis and mass, mammary gland hyperplasia, menstrual syndrome in gynecology, habitual abortion, ectopic pregnancy, infertility in obstetrics, hyperlipidemia, myocarditis, thrombophlebitis in cardiovascular system, etc. And asthma, thyroid disease, low back pain, prostatitis, menopausal syndrome, etc. [0003] Pharmacological research on the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K36/73A61K36/71A61K36/54A61K36/076A61P15/00A61P9/00A61P3/06A61P13/08
Inventor 赵凯苑洪忠肖宝华林涛李雪明高文倩
Owner 江西欧氏药业有限责任公司