Toxicity T cell position vaccine of the cell for treating Hepatitis B and the preparing method
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
- Publication Date
- 2007-09-19
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
Technical field:
[0001] The invention relates to the technical field of biomedical engineering, and is a hepatitis B therapeutic cytotoxic T cell epitope vaccine and a preparation method thereof. Background technique:
[0002] Hepatitis B virus (HBV) is a hepatotropic DNA virus that is prone to chronic infection after infecting the human body. It is the first cause of liver cirrhosis and primary liver cancer in Southeast Asian countries and regions, including my country. The treatment drugs for HBV infection currently mainly rely on IFN-α and nucleoside analogues. None of these drugs can completely eliminate the virus, and the long-term efficacy is poor. Therapeutic vaccine is a specific immunotherapy that has emerged in the past decade. Animal and clinical studies have shown that vaccination of such vaccines can enhance the cellular immune response of the infected person (or animal), thereby inhibiting virus replication. Summary of the invention:
[0003] The purpose of the pre...