Preparation method of enema for curing gynecology inflammation

A technology for gynecological inflammation and enema, which is applied in the field of preparation of traditional Chinese medicine compositions, can solve the problems of large dosage, low bioavailability, easy recurrence of illness, etc., achieves improved bioavailability, improved therapeutic effect, and avoided first pass effect of effect

Active Publication Date: 2008-05-14
广东德鑫制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the modern medical treatment of gynecological inflammation is mainly treated with antibiotics, but antibiotics often produce drug-resistant bacteria, and the curative effect is not good, which makes the disease prone to repeated attacks
[0003] Fuyankang Tablets is a statutory Chinese patent medicine variety, a national second-class protected variety of traditional Chinese medicine, has a better curative effect on gynecological inflammation, and has a wider clinical application basis; existing Fuyankang Tablets have modified dosage forms such as: Fuyankang Pills, Fuyankang Capsules, Fuyankang Granules, etc. are made by changing the dosage form based on the original Fuyankang Tablet technology. The above dosage forms are all administered orally, with low bioavailability. In clinical use, there are large dosages and slow onset of effects. Shortcomings such as a long course of treatment cannot meet the needs of the majority of patients, and during preparation, the filtrate needs to be concentrated, and the long-term high temperature action causes the active ingredients to decompose and denature. , slow onset, poor therapeutic effect, long course of treatment

Method used

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  • Preparation method of enema for curing gynecology inflammation
  • Preparation method of enema for curing gynecology inflammation
  • Preparation method of enema for curing gynecology inflammation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0131] (1) Select the following raw materials in parts by weight: 60 parts of red peony root, 100 parts of smilax gram, 60 parts of three-lens (vinegar broiled), 60 parts of Chuanmuzi (fried), 60 parts of zedoary turmeric (vinegar broiled), Corydalis (Vinegar broiled) 60 parts, Gorgon (stir-fried) 100 parts, Angelica 100 parts, Sophora flavescens 60 parts, Cyperus rotundus (vinegar broiled) 40 parts, Phellodendron chinensis 60 parts, Salvia miltiorrhiza 100 parts, Chinese yam 120 parts, and some of them The Chinese yam is crushed into 40-100 mesh fine powder for use;

[0132] (2) Red peony roots, Smilax glabra, Sanleng, Chuan neem, Corydalis, Gorgon, Angelica, Sophora flavescens, Cyperus rotundus, Cork, and Dan are decocted in water for three times. Add 5-20 times the amount of water for the first time. Decoction for 2 hours, add 5-20 times the amount of water for the second time, decoct for 1 hour, add 5-20 times the amount of water for the third time, decoct for 1 hour, combine s...

Embodiment 2

[0140] (1) Select the following raw materials in parts by weight: 60 parts of red peony root, 100 parts of tuckahoe gram, 60 parts of three-lens (vinegar broiled), 60 parts of Chinese neem (fried), 60 parts of zedoary turmeric (vinegar broth) Corydalis (Vinegar broiled) 60 parts, Gorgon (stir-fried) 100 parts, Angelica 100 parts, Sophora flavescens 60 parts, Cyperus rotundus (vinegar broiled) 40 parts, Phellodendron chinense 60 parts, Salvia miltiorrhiza 100 parts, Chinese yam 120 parts, and some of them Crush the yam and yam into 40-100 mesh fine powder for later use;

[0141] (2) Red peony roots, Smilax glabra, Sanleng, Chuan neem, Corydalis, Gorgon, Angelica, Sophora flavescens, Cyperus rotundus, Cork, and Dan are decocted in water for three times. Add 5-20 times the amount of water for the first time. Decoction for 2 hours, add 5-20 times the amount of water for the second time, decoct for 1 hour, add 5-20 times the amount of water for the third time, decoct for 1 hour, combin...

Embodiment 3

[0148] (1)~(2) The steps are the same as in Example 1.

[0149] (3) Mix the above-mentioned filtrate with fine medicinal material powder and preservative sodium benzoate 0.5 g / 100mL, add water to dilute to 6 g of original medicinal material per 100 ml, sterilize, cool, and set aside;

[0150] (4) Aseptically dispensed into 300mL plastic bottles, packaged to obtain liquid enema;

[0151] (5) If the dry powder type is prepared, the process route includes: concentrating the collected filtrate to a clear ointment with a certain density, adding the above-mentioned medicinal powder, stirring uniformly, drying, adding an appropriate amount of auxiliary materials, the auxiliary materials used are the same as in Example 1, crushing , Sterilization, packaging and other processes to make dry powder enema.

[0152] (6) If the dry granular type is prepared, the process route includes: concentrating the collected filtrate to a clear cream with a certain density, adding the above-mentioned medic...

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PUM

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Abstract

The invention relates to a preparation method of enemas for gynecological inflammation, which comprises the following steps. Firstly, select a plurality of pharmaceutical ingredients in weight ratio-sixty shares of red peony root, one hundred shares of rhizome smilacis glabrae, sixty shares of rhizoma sparganii, sixty shares of Szechwan chinaberry fruit, sixty shares of rhizome zedoariae, sixty shares of rhizome corydalis, one hundred shares of fried foxnut, one hundred shares of Chinese angelica, sixty shares of light yellow sophora root, forty shares of nutgrass galingale rhizome, sixty shares of amur corktree bark, one hundred shares of Danshen root, and one hundred and twenty shares of Chinese yam. Secondly, grind the rhizome zedoariae and the Chinese yam into fine powder of forty to one hundred meshes for future use, and decoct the rest medicinal herbs with water for three times: at the first time, add water by five to twenty times in weight and decoct for two hours; at the second time, add water by five to twenty times in weight and decoct for one hour; at the third time, add water by five to twenty times in weight and decoct for one hour, and then mix the three decoction solutions and get the filtrate after filtering. Thirdly, concentrate the filtrate. And finally add the fine powder of the rhizome zedoariae and the Chinese yam into the concentrated filtrate to sterilize, cool down and the enema is made. The preparation method can increase the active ingredients of the medicine remarkably, and the medicine combination in the preparation method is characterized in high content of crude drug, and a fast but good therapeutic effect.

Description

Technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition for treating gynecological inflammation, in particular to a preparation method of an enema. Background technique [0002] Gynecological inflammation mainly refers to the inflammation of female reproductive organs, including female pelvic inflammatory disease, adnexitis, cervicitis, vaginitis, urethritis, etc. caused by various reasons. It is a common disease in gynecology. The prevalence of adult women is as high as 80%. Gynecological inflammation can spread to nearby organs such as the cervix, uterus, appendages, and cause infection; chronic inflammation can also cause infertility or miscarriage. The disease seriously affects women's work, study and life, and brings heavy mental burden and economic pressure to patients, families and society. At present, the modern medical treatment of gynecological inflammation is mainly treated with antibiotics, but antibiotics oft...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/08A61K9/14A61K9/16A61P15/00
Inventor 蒋晨光景运条蒋东旭黄鸣清陈长青
Owner 广东德鑫制药有限公司
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