Preparation of quaternary ammonium N-carboxyetbyl chitosan

Abstract

The invention relates to a quaternization N-ethyl chitosan, which is a novel chitosan ramification with a good water-solubility, bacteriostasis, moisture absorption, moist storage and emulsification stability. The preparation process is characterized in that: under the pH of 3.0 to 12.0, the chitosan of the deacetylation of 30 percent to 90 percent is reacted with pyruvic acid and malonaldehydic acid to generate a chitosan Schiff base, and is deoxidized by sodium borohydride, potassium borohydride, sodium borohydride cyanoacrylate, cyano-group sodium borohydride and the mixture to obtain the N-ethyl chitosan; the N-ethyl chitosan in alcohol medium is processed by alkali, and is modified by glycidyl trimethyl ammonium chloride or 3-chlorine -2-hydroxy trimethyl ammonium chloride so as to get N-ethyl chitosan admixture with quaternization; the admixture is washed and dissolved by methyl alcohol or ethanol solution, then dialysis desalination, concentration in decompression or atmospheric pressure, absolute ethyl alcohol, or acet sedimentation and dehydration are conducted, finally the admixture is arranged in a vacuum airer at 60 DEG C to 150 DEG C for drying for vacuum freeze drying until the water volume is less than 10 percent.

Description

technical field [0001] The quaternized N-carboxyethyl chitosan involved in the present invention includes quaternized N-(1-carboxyethyl) chitosan and quaternized N-(2-carboxyethyl) chitosan, It is a new type of amphoteric chitosan derivative in the field of polysaccharide biochemistry in the field of biochemistry. Background technique [0002] As the only alkaline natural amino polysaccharide biopolymer compound, chitosan is second only to cellulose in annual production. The production of chitosan is generally based on the chitin obtained from the shells of crustaceans or insects through acidification, alkalization and decolorization as raw materials, and deacetylated at high temperature in the presence of concentrated alkali. Most of the amino groups in the molecular structure of chitosan exist in the form of free amino groups and have good reactivity, so the application performance of chitosan is significantly improved and improved compared with chitin. Chitosan not only...

AI Technical Summary

Problems solved by technology

In the method for chemically modifying chitosan to obtain chitosan derivative products with strong amphoteric characteristics for the purpose of increasing the positive charge and negative charge of chitosan, it only involves Graft quaternization and direct quaternization of carboxymethyl chitosan and carboxymethylation of chitosan with 2-hydroxypropyltrimethylammonium chloride and chitosan trimethylammonium chloride, which allow At present, the method aimed at improving the charging performance and application performance of chitosan is actually used to chemically modify chitosan to obtain chitosan derivative products, which still have insufficient application performance.