A method for synthesizing an isobutyraldehyde catalyst by using methyl alcohol and ethanol in one step relates to a preparation method for the catalyst. The preparation method comprises the following steps of: dissolving a solubility vanadic salt and ferric salt in an aqueous solution, adding citric acid and one or two soluble salts of Ce, Zr and La, then stirring and evaporating a solvent, drying, molding and roasting after solvent evaporation is ended, and preparing the oxide catalyst, wherein the charging manner of a V salt solution and citric acid, Fe, Ce, Zr, La solutions is a positive addition method, a reverse addition method or a combining addition method, the evaporation temperature of the solvent is 30-95 DEG C, V is an active component, Fe, Ce, Zr and La are auxiliaries, a V metal salt is a vanadium soluble salt, and Fe, Ce, Zr and La salts are corresponding nitrates, the drying temperature is 80-150 DEG C, and the roasting temperature is 350-800 DEG C. The prepared product prepared by the method comprises main products such as high value-added acetaldehyde and propionaldehyde apart from isobutyraldehyde and few other by-products; and the catalyst has good stability, high activity and high selectivity.