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Pharmaceutical composition for treating climacteric syndrome and preparation method thereof

A technology of composition and syndrome, applied in the fields of pharmaceutical composition and its preparation, pharmaceutical composition for treating climacteric syndrome and its preparation, which can solve the problems that climacteric syndrome has no ideal treatment means and cannot delay the function decline of various organs of the body Speed ​​and other issues

Inactive Publication Date: 2008-09-24
TIANKE RENXIANG TECH BEIJING
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no ideal treatment for menopausal syndrome clinically, and symptomatic treatments such as sex hormone therapy, α2 receptor agonists, β-adrenergic blockers, sedative-anxiety agents, and antidepressants are still the main treatments. Relief of clinical symptoms has a certain curative effect, but it cannot delay the decline of the function of various organs in the body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Prescription composition:

[0028] Rehmannia glutinosa 100g Cistanche 100g Astragalus 80g Epimedium 60g

[0029] Psoralen 60g Atractylodes macrocephala 40g Angelica 60g Achyranthes bidentata 40g

[0030] Paeoniae Alba 40g Bupleurum 40g

[0031] Honey (refined) 100g sucrose 50g

[0032] Make a total of 1000ml

[0033] Preparation:

[0034] (1) Take Cistanche Herba, Epimedium, and Psoraleae, grind them into coarse powder, extract with 10 times the amount of 85% ethanol under reflux for 2 hours, and filter the extracted alcohol solution; add 8 times the amount of 85% ethanol to extract under reflux for 2 hours , extract the alcohol solution and filter; add 8 times the amount of 85% ethanol to the dregs of the medicine for reflux extraction for 2 hours, extract the alcohol solution and filter, combine the filtrates, recover ethanol under reduced pressure and concentrate to a clear paste with a relative density of 1.05, and set aside;

[0035] (2) Take Rehmannia glutino...

Embodiment 2

[0038] Prescription composition:

[0039] Rehmannia glutinosa 200g Cistanche 200g Astragalus 160g Epimedium 120g

[0040] Psoralen 120g Atractylodes macrocephala 80g Angelica 120g Achyranthes bidentata 80g

[0041] Paeoniae Alba 80g Bupleurum 80g

[0042] Starch 85g

[0043] A total of 1000 capsules were made

[0044] Preparation:

[0045] (1) Take Cistanche Herba, Epimedium, and Psoraleae, grind them into coarse powder, extract with 10 times the amount of 85% ethanol under reflux for 2 hours, and filter the extracted alcohol solution; add 8 times the amount of 85% ethanol to extract under reflux for 2 hours , extract the alcohol solution and filter; add 8 times the amount of 85% ethanol to the dregs of the medicine for reflux extraction for 2 hours, extract the alcohol solution and filter, combine the filtrates, recover ethanol under reduced pressure and concentrate to a clear paste with a relative density of 1.25, and set aside;

[0046] (2) Take Rehmannia glutinosa, As...

Embodiment 3

[0050] Prescription composition:

[0051] Rehmannia glutinosa 100g Cistanche 100g Astragalus 80g Epimedium 60g

[0052] Psoralen 60g Atractylodes macrocephala 40g Angelica 60g Achyranthes bidentata 40g

[0053] Paeoniae Alba 40g Bupleurum 40g

[0054] A total of 1000 capsules were made

[0055] Preparation:

[0056] (1) Take Cistanche Herba, Epimedium, and Psoraleae, grind them into coarse powder, extract with 10 times the amount of 85% ethanol under reflux for 2 hours, and filter the extracted alcohol solution; add 8 times the amount of 85% ethanol to extract under reflux for 2 hours , extract the alcohol solution and filter; add 8 times the amount of 85% ethanol to the dregs to reflux for extraction for 2 hours, extract the alcohol solution and filter, combine the filtrates, recover ethanol under reduced pressure and concentrate to a clear paste with a relative density of 1.35, and set aside;

[0057] (2) Take Rehmannia glutinosa, Astragalus membranaceus, Atractylodes ma...

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PUM

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Abstract

The invention provides a drug composition for curing climacteric syndrome and a preparation method thereof. The drug is made of raw medicines such as radix rehmanniae preparata, broomrape, milk veteh, epimedium and psoralea and can be processed into any one of clinically acceptable oral liquid, syrup, tablets, capsules, granular formulation and soft capsules. The drug composition can replenish vital essence to tonify the kidney, relieves liver qi stagnation, invigorate spleen and stomach, replenish qi and blood, activate blood and dissolve stasis, is used for curing the climacteric syndrome with the symptoms such as insomnia, amnesia, dizziness, tinnitus, inappetence, soreness-tired of waist and knee, depression, irritability, testiness and sexual function decrement and also can delay aging, enhance immunity and prevent osteoporosis.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for treating menopausal syndrome and a preparation method thereof, belonging to the technical field of new medicines. Background technique [0002] Menopausal syndrome is a series of diseases caused by autonomic nervous system dysfunction due to menopause, and the main factor is the symptoms caused by the decrease of hormone level. The main clinical manifestations are difficulty in falling asleep, insomnia, dizziness, headache, tinnitus, loss of appetite, fatigue, memory loss, inability to concentrate, depression, anxiety, tension, emotional instability, irritability, hot flashes, night sweats, suspicious, Auditory hallucinations, hallucinations, menstrual cycle disorders, sexual dysfunction, etc. [0003] Menopause is a necessary life stage for human beings to transition from middle age to old age. Due to the changes i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/20A61K9/48A61K9/16A61K9/10A61P15/12
Inventor 王丽娟
Owner TIANKE RENXIANG TECH BEIJING
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