Preparation of 1,3,5-tri(2,6-dinitro- trifluoromethylphenoxy) benzene
A technology of trifluoromethyl phenoxy and trifluoromethyl halogenated benzene is applied in the field of preparation of aromatic organic compounds and achieves the effects of high yield and purity, few types of use and simple operation
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Embodiment 1
[0028] 12.6 grams (0.10 moles) of 1,3,5-pyrogallol, 86.6 grams (0.32 moles) of 2,6-dinitro-4-trifluoromethylchlorobenzene, 110.4 grams (0.80 moles) of potassium carbonate , 800 milliliters of N,N-dimethylformamide and 80 milliliters of benzene were put into the reaction kettle, stirred, heated to reflux and separated from water for 18 hours, concentrated the reaction liquid, recovered the solvent for recycling, cooled the reactant system, added water, Separate out solid product, wash 2~3 times with hot water, dry, obtain 80.6 grams of 1,3,5-three (2,6-dinitro-4-trifluoromethylphenoxy) benzene crystal product, purity It is 99.5%. According to the actual amount of 1,3,5-tri(2,6-dinitro-4-trifluoromethylphenoxy)benzene and the theoretical amount (82.8 grams), 1,3, The yield of 5-tris(2,6-dinitro-4-trifluoromethylphenoxy)benzene was 97.4%.
Embodiment 2
[0030] 12.6 grams (0.10 moles) of 1,3,5-pyrogallol, 100.8 grams (0.32 moles) of 2,6-dinitro-4-trifluoromethylbromobenzene, 55.2 grams (0.40 moles) of potassium carbonate , 700 milliliters of N, N-dimethylacetamide, 180 milliliters of benzene and 20 milliliters of xylene were put into the reaction kettle, stirred, and heated to reflux for water separation and reaction for 6 hours, then concentrated the reaction solution, recovered the solvent for recycling, and cooled the reaction After adding water, the solid product was separated out, washed 2 to 3 times with hot water, and dried to obtain 74.9 grams of 1,3,5-tris(2,6-dinitro-4-trifluoromethylphenoxy)benzene Crystalline product, the purity is 99.4%, according to the actual amount of 1,3,5-three (2,6-dinitro-4-trifluoromethylphenoxy) benzene obtained and the theoretical amount (82.8 grams), calculated The yield of 1,3,5-tris(2,6-dinitro-4-trifluoromethylphenoxy)benzene was 90.5%.
Embodiment 3
[0032] 12.6 grams (0.10 moles) of 1,3,5-pyrogallol, 81.2 grams (0.30 moles) of 2,6-dinitro-4-trifluoromethylchlorobenzene, 55.2 grams (0.40 moles) of potassium carbonate , 10.6 grams (0.10 moles) of sodium carbonate, 252 milliliters of N-methyl-2-pyrrolidone, 400 milliliters of benzene and 104 milliliters of dichlorobenzene were put into the reaction kettle, stirred, and heated to reflux for water separation for 16 hours, then concentrated the reaction liquid, recover the solvent for recycling, cool the reactant system, add water, precipitate a solid product, wash with hot water 2 to 3 times, and dry to obtain 76.6 grams of 1,3,5-tri(2,6-dinitro-4 -trifluoromethylphenoxy)benzene crystal product, the purity is 99.2%, according to the actual obtained 1,3,5-three (2,6-dinitro-4-trifluoromethylphenoxy)benzene Quantity and theoretical yield (82.8 g), the calculated yield of 1,3,5-tris(2,6-dinitro-4-trifluoromethylphenoxy)benzene was 92.5%.
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