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Nano-scale chitosan and latex coblended antibiont and preparation method thereof

A chitosan and nano-scale technology, which is applied in the field of nano-scale chitosan and latex blended antibacterial substances and its preparation, can solve the problems of chitosan not showing antibacterial properties, long antibacterial latex time, and human health hazards , to achieve the effect of easy mixing with latex, solving potential hazards, and long solution time

Inactive Publication Date: 2008-12-03
TAIYUAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

To solve the potential harm to human health caused by the use of chemical reagents as latex antibacterial components in the prior art; the preparation of antibacterial latex takes a long time and the process is complicated; and when using chitosan, it fails to reflect its antibacterial properties

Method used

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  • Nano-scale chitosan and latex coblended antibiont and preparation method thereof
  • Nano-scale chitosan and latex coblended antibiont and preparation method thereof
  • Nano-scale chitosan and latex coblended antibiont and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0037](1) 0.04g chitosan was dissolved in 20ml 2% acetic acid solution, placed on a magnetic stirrer and stirred for 40min;

[0038] (2) After standing for 5 minutes to defoam, add 3.35 mg of dispersant sodium polyphosphate until the solution is milky white;

[0039] (3) Use sodium hydroxide solution to adjust the pH of the solution to 5.0-6.0, and then use ammonia water to adjust the pH to 8.5-9.0;

[0040] (4) Filter 10ml of latex with 80 mesh molecular sieves, pour it into a three-hole flask, and use an electric stirrer to stir for 10min at a speed of 60r / min to remove the ammonia therein;

[0041] (5) pour 10ml into the nanoscale chitosan solution prepared in the third step, feed nitrogen;

[0042] (6) Stir for 3h at a rotating speed of 60r / min;

[0043] (7) Take it out after the stirring is completed, and form a film after standing for 48 hours.

[0044] Obtained by the above-mentioned preparation method to be made up of nano-scale chitosan, latex and sodium polyphosph...

Embodiment 2

[0046] According to the processing method of embodiment 1, the difference of embodiment 2 is: the ratio of the molar mass of nanoscale chitosan and latex is 1: 5; Be dissolved in the acetic acid solution of 20ml 2%; Stir under the rotating speed of 100r / min 2h. The molar mass ratio of nanoscale chitosan and latex obtained is: 1:5~2:1; the ratio of molar mass of sodium polyphosphate to chitosan is: 1:200~1:50 nanoscale chitosan Antimicrobial blend of sugar and latex.

Embodiment 3

[0048] According to the processing method of embodiment 1, the difference of embodiment 3 is: the ratio of the molar mass of nanoscale chitosan and latex is 2: 1; Be dissolved in the acetic acid solution of 20ml 2%; Stir under the rotating speed of 80r / min 4h. The molar mass ratio of nanoscale chitosan and latex obtained is: 1:5~2:1; the ratio of molar mass of sodium polyphosphate to chitosan is: 1:200~1:50 nanoscale chitosan Antimicrobial blend of sugar and latex.

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Abstract

The invention discloses a nano-scale chitosan and latex co-mixed antibacterial material and the preparation method thereof. The co-mixed antibacterial material contains nano-scale chitosan, latex, and sodium polyphosphate, wherein the molar ratio of chitosan to latex is 1:5 to 2:1, and the molar ratio of sodium polyphosphate to chitosan is 1:200 to 1:50. The preparation method of the co-mixed antibacterial material comprises the following steps: nano-crystallizing chitosan and blending with the latex. The preparation method can improve the antibacterial performance of latex without changing the original mechanical performance of latex, and has simple and rapid operation and no usage of toxic chemical reactant. The bacterial inhibition ring test shows that the co-mixed material has remarkable effect on inhibiting Escherichia coli and Staphylococcus aureus, and the co-mixed material can be cultured at 37 DEG C to form a bacterial inhibition ring equal to or larger than 10 mm. The co-mixed material has remarkable bacterial inhibition effect, low cost and no harm to human body, and can be used in the field of medical materials.

Description

technical field [0001] The invention relates to a chitosan and latex blended antibacterial substance and a preparation method thereof, in particular to a nanoscale chitosan and latex blended antibacterial substance used in medicine and a preparation method thereof. Background technique [0002] In the existing preparation of latex with antibacterial properties, quaternary ammonium salts, Ag ions, tetramethyldithiooxamide (TMDTO), etc. are usually used as antibacterial agents to graft or blend with latex to make latex antibacterial. [0003] Chitosan is the only alkaline polysaccharide that exists in large quantities in the biological world. It has attracted people's attention for its unique biocompatibility, biodegradability, antibacterial properties, non-toxicity, biological activity and physical and chemical properties. , Textile, printing and dyeing, papermaking and medicine and other fields have broad application prospects. [0004] Publication No. CN100351293 "Preparat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L5/08C08L101/00C08K3/32A01P1/00C08J5/18
Inventor 魏丽乔许并社米振国张利贾鹏侯莹
Owner TAIYUAN UNIV OF TECH
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