Method for preparing fungal polysaccharide

A fungal polysaccharide and vacuum technology, applied in the field of preparation of fungal polysaccharides, can solve the problems of large solvent consumption, environmental pollution, low energy utilization rate, etc., and achieve the effect of saving steam consumption, shortening the extraction cycle, and remarkable energy saving effect

Inactive Publication Date: 2009-05-20
HENAN UNIVERSITY OF TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the production process, it will cause a great waste of energy and funds. For example, when using hot water for extraction, the hot water will continue to evaporate from the tank during the heating process, which requires us to keep replenishing water and Heating, so that a large amount of solvents and energy are wasted; Another example is when using organic solvents (such as alcohol, acetone) to extract, along with the continuous volatilization of organic solv...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A method for preparing fungal polysaccharides, comprising the following processing steps:

[0026] (1) Raw material crushing and extractant mixing

[0027] Wash and dry the raw materials for extracting and preparing fungal polysaccharides (lotus fungi, shiitake mushrooms, and Hericium erinaceus) at low temperature (30°C), then crush them into 60-100 μm particles, and mix them with extractant water at a mass ratio of 1:3.5 Uniform;

[0028] (2) Extraction

[0029] The above-mentioned raw materials and extractant mixed solution are subjected to solvent multi-stage circulation dynamic thermal reflux extraction in a multi-functional extractor, the extraction temperature is 35 ° C, pH = 4.5, and the solvent reflux rate is 5%. Reflux) extract 40 minutes;

[0030] (3) Filtration and concentration

[0031] The above-mentioned extraction solution extracted for a certain period of time is directly vacuum-transported to an external circulation heating double-effect vacuum conc...

Embodiment 2

[0037] The same as the steps of Example 1, the difference is:

[0038] (1) Put the raw materials for extracting and preparing fungal polysaccharides (lotus fungi, shiitake mushrooms, and Hericium erinaceus) at 50°C and dry them, then crush them into 2500-3000 μm particles, and mix them with extractant water at a mass ratio of 1:8 ;

[0039] (2) The extraction conditions are: extraction temperature 100°C, pH=6.5, solvent reflux rate 15% under the conditions of reflux (using 2-stage solvent circulation dynamic heat reflux) for extraction for 70 minutes;

[0040] (3) Concentration: Concentrate for 3 hours at a vacuum of 0.05MPa and a temperature of 65°C;

[0041] (4) Alcohol precipitation: add 3 times of 95% food grade or above alcohol according to the volume ratio, stir evenly and let stand for 80 minutes;

[0042] (5) Drying: Add 8 times of distilled water or other solvents to the above-mentioned alcohol precipitates according to the mass ratio and stir to dissolve them, and ...

Embodiment 3

[0044] The same as the steps of Example 1, the difference is:

[0045] (1) Put the raw materials for extracting and preparing fungal polysaccharides (lotus fungi, shiitake mushrooms, and Hericium erinaceus) at 65°C and dry them, then crush them into particles of 6500-7000 μm, and mix them with the extractant water at a mass ratio of 1:12 ;

[0046] (2) The extraction conditions are: extraction temperature 80°C, pH=8.5, solvent reflux rate 28% under the conditions of reflux (using 3-stage solvent circulation dynamic heat reflux) for extraction for 90 minutes;

[0047] (3) Concentration: Concentrate for 2 hours at a vacuum of 0.065MPa and a temperature of 80°C;

[0048] (4) Alcohol precipitation: add 5 times of 95% food grade or above alcohol according to the volume ratio, stir evenly and let stand for 120 minutes;

[0049] (5) Drying: Add 15 times of distilled water or other solvents to the above-mentioned alcohol precipitate according to the mass ratio and stir to dissolve i...

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PUM

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Abstract

The invention discloses a method for preparing fungi polysaccharide, namely a multi-stage dissolvent-cycle dynamic-thermal-reflux extraction condensation method. The method comprises the technological steps of raw material crushing, mixing with a solvent, extraction, condensation, deposition in alcohol, filtering and drying so as to obtain a finished product. The method for preparing fungi polysaccharide integrates extraction, condensation, solvent recovery and the like together, and is completely carried out in an enclosed system, without any bad occurrence of escaping, steaming, leakage and dripping, etc. The production practice shows that the method can shorten the extraction cycle by 50 percent to 85 percent so as to improve the production rate; the ration between raw material to solvent can be reduced to 1:3-8 (as the traditional method has a ration between raw material and solvent higher than 1:20), and the amount of an extractant used can also be saved by 25 percent to 80 percent; primary/secondary steam can be put into fullplay and cooling water is saved so that the effect of energy conservation is very significant. Compared with the traditional method, the method can save 30 percent to 70 percent of steam amount; and the medical material does not need to be crushed finely, which is favorable to the further operation. The method can be largely applied to the development and production of the fungi polysaccharide and other related polysaccharides or natural medical materials.

Description

technical field [0001] The invention relates to a method for preparing fungal polysaccharides. Background technique [0002] Internationally, edible and medicinal fungal polysaccharides are called "biological response modifiers" (Biological Response Modifier, referred to as BRM). In recent years, with the continuous emergence of new technologies and methods in biochemistry, bioengineering, and biopolymer research, the research on polysaccharides of edible and medicinal fungi has developed rapidly at home and abroad. At present, edible and medicinal fungal polysaccharides have become one of the research hotspots in the fields of biochemistry, molecular biology, medicine, pharmacy, and food science. Although people have conducted extensive and in-depth research on the structure, biological activity, and pharmacological functions of fungal polysaccharides, how to efficiently prepare fungal polysaccharides has not attracted much attention. At present, the preparation methods o...

Claims

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Application Information

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IPC IPC(8): C08B37/00
Inventor 王卫国赵永亮何泓良伊首璞李若
Owner HENAN UNIVERSITY OF TECHNOLOGY
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