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Preparation for treating flat wart and preparation method thereof

A technology of flat warts and preparations, applied in the field of medicine and health, which can solve the problems of redness, swelling, irritation, unsuitable use of flat warts, etc., and achieve the effect of non-irritation, strong inhibitory effect, and no discomfort

Inactive Publication Date: 2009-06-24
泰安诺和诺泰生物制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are many external treatment methods for flat warts. Topical retinoic acid or 5-FU spot application, generalized patients are often eager to treat the disease, and a large amount of application can easily cause redness, swelling and irritation at the application site, and even temporary pigmentation spots. Patients are required to It has good compliance and is generally not suitable for flat warts on the face

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take Cyperus officinalis 2g, Equisetum 30g, Curcuma 1g, Daqingye 50g, Banlangen 1g, α-2b interferon 2.0*10 7 U. Sodium carboxymethyl cellulose 1g, glycerin 50g, ethyl p-hydroxybenzoate 0.05g, first put Cymbidium, Equisetum, Curcuma Radix, Daqingye, Banlangen into a container, add 100ml of water, soak for 30min and boil for 10min, The medicinal solution was collected by filtration and concentrated to 50ml, then added sodium carboxymethyl cellulose, glycerol, and ethyl p-hydroxybenzoate to mix evenly, autoclaved at 100°C for 40min, naturally cooled to room temperature, and added α-2b interferon solution , slowly stirred into a gel, and packed in medicinal aluminum tubes, each 12g.

Embodiment 2

[0028] Take Cyperus officinalis 5g, Equisetum 18g, Curcuma 6g, Daqingye 40g, Banlangen 10g, α-2b interferon 1.7*10 7 U. Sodium carboxymethyl cellulose 6g, glycerin 10g, ethyl p-hydroxybenzoate 0.07g, first put Cymbidium, Equisetum, Curcuma Radix, Daqingye, Banlangen into a container, add 150ml of water, soak for 25min and boil for 20min, The medicinal solution was collected by filtration and concentrated to 80ml, then added sodium carboxymethyl cellulose, glycerol, and ethyl p-hydroxybenzoate to mix evenly, autoclaved at 105°C for 35min, cooled to room temperature naturally, and added α-2b interferon solution , slowly stirred into a gel, and packed in medicinal aluminum tubes, each 12g.

Embodiment 3

[0030] Take Cyperus officinalis 10g, Equisetum 5g, Curcuma 10g, Daqingye 6g, Banlangen 6g, α-2b interferon 1.8*10 7 U, 4 g of sodium carboxymethyl cellulose, 16 g of glycerin, and 0.1 g of ethyl p-hydroxybenzoate. First, put Cyperus officinalis, Equisetum, Curcuma, Daqingye and Banlangen into a container, add 200ml of water, soak for 20min, boil for 30min, filter and concentrate the liquid to 90ml, then add sodium carboxymethylcellulose, glycerin, p-hydroxybenzene Ethyl formate is mixed evenly, autoclaved at 115°C for 30 minutes, cooled to room temperature naturally, added with α-2b interferon solution, slowly stirred into a gel, and packed in medicinal aluminum tubes, each 12g.

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PUM

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Abstract

The invention discloses a reagent for treating flat wart and a method for preparing the same. The reagent consists of the following drug-effect raw materials by weight: 2 to 50g of Nutgrass Galingale Rhizome, 1 to 30g of common scouring rush herb, 1 to 100g of Rhizoma Zedoariae, 1 to 50g of isatis leaf, 1 to 50g of isatis root, 1.5*10<7> to 2.0*10<7>U of alpha-2b interferon, 1 to 20g of sodium cellulose glycolate, 2 to 50g of glycerin, and 0.05 to 0.2g of ethyl p-hydroxybenzaote. By the combination of the traditional Chinese medicine principle and the alpha-2b interferon antivirus concept, the invention develops the reagent for treating the flat wart, which consists of the alpha-2b interferon and external-use anti-virus compositions, and the reagent has broad-spectrum antivirus activity and immunity adjusting function; and in the clinical treatment, the average effect-starting time is shorter than that of the 5 percent imiquimod cream; moreover, the reagent also has the advantages of stability, reliability, no pungency, strong inhibition on HSV, no uncomfortable feeling after application, simple preparation method and low cost.

Description

technical field [0001] The invention relates to the field of medicine and health, in particular to a preparation for treating flat wart and a preparation method thereof. Background technique [0002] Flat warts are flat, skin-colored, reddish, or brownish papules that commonly appear on the face, backs of hands, and forearms of adolescents and affect appearance. At present, there are many treatment methods, but the efficacy for generalized flat warts varies. Flat warts are caused by human papillomavirus infection of the epidermis. Its viral replication is highly dependent on keratinocyte differentiation. Studies have shown that the epidermis of the flat wart is obviously hyperkeratotic, the spinous layer is hypertrophic, the granular layer is uniformly thickened, and the keratinocyte cells are obviously basket-shaped due to the formation of vacuoles. [0003] There are many topical treatment methods for flat warts. Topical retinoids or 5-FU are applied on a spot. Patients...

Claims

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Application Information

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IPC IPC(8): A61K38/21A61K47/38A61K9/00A61P17/12A61P31/20A61K36/906
Inventor 毕玉山刘振平张瑞琛
Owner 泰安诺和诺泰生物制药有限公司
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