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Method for extracting and separating flavone and anthocyanidin from elder fruit

A separation method and elderberry technology are applied in pharmaceutical formulations, medical preparations containing active ingredients, plant/algae/fungus/moss components, etc., which can solve the problem of low recovery rate and content of product target components, troublesome raw material processing, and product Problems such as poor color and luster, to achieve the effect of easy industrial production, simplified steps, and industrialized production

Inactive Publication Date: 2009-06-24
SHAANXI MINGRUI NATURAL PRODS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] The present invention provides a method for extracting and separating flavonoids and anthocyanins from elderberry fruit, so as to overcome the problems of troublesome raw material processing, low recovery rate and content of product target components and poor product color in the prior art

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. Extraction:

[0031] Accurately weigh 500kg of fresh elderberry fruit (anthocyanin content: 0.41%), crush it with a fruit crusher to obtain 499kg of crushed pulp, directly put it into the extraction tank with 5000kg of purified water added in advance, open and stir (rotation speed 32rpm / h) , then adjust PH3 with hydrochloric acid (acidity meter detection) while stirring, heat to 50 ° C with steam, and keep the temperature at 48 ~ 52 ° C under the condition of stirring, soaking and extracting for 5 hours. Press filter by plate and frame filter press to obtain 5210kg of clarified extraction filtrate. Detected by ultraviolet detector (UV): the content of anthocyanin in the extract is 0.038%, the calculated amount of pure anthocyanin is: 1.98kg; the recovery rate of anthocyanin extraction is 96.6%.

[0032] 2. Adsorption and elution of medium and low pressure macroporous resin adsorption column:

[0033] The obtained 5210kg elderberry fruit was leached, filtered and th...

Embodiment 2

[0039] 1. Extraction:

[0040] Accurately weigh 500kg of fresh elderberry fruit (anthocyanin content: 0.41%), crush it with a fruit crusher to obtain 498kg of crushed pulp, directly put it into the extraction tank with 5000kg of purified water added in advance, open and stir (rotation speed 32rpm / h) , then adjust the pH to 3.5 with sulfuric acid while stirring (detected by acidity meter), heat it to 50°C with steam, and keep the temperature at 48-52°C for stirring, soaking and extracting for 4 hours. Pass through the plate and frame filter press together to obtain 5200kg of clarified extraction filtrate. Detected by ultraviolet detector (UV): the content of anthocyanin in the extract is 0.038%, the calculated amount of pure anthocyanin is: 1.976kg; the recovery rate of anthocyanin extraction is 96.4%.

[0041] 2. Adsorption and elution of medium and low pressure macroporous resin adsorption column:

[0042]The obtained 5200kg elderberry fruit is leached, and the clarified li...

Embodiment 3

[0048] 1. Extraction:

[0049] Accurately weigh 500kg of fresh elderberry fruit (anthocyanin content: 0.41%), crush it with a fruit crusher to obtain 498kg of crushed pulp, directly put it into the extraction tank with 4500kg of purified water added in advance, open and stir (rotation speed 32rpm / h) , then adjust PH3 with hydrochloric acid (acidity meter detection) while stirring, heat to 50 ° C with steam, and keep the temperature at 50 ~ 55 ° C under the condition of stirring, soaking and extracting for 5 hours. Press filter by plate and frame filter press to obtain 4900kg of clarified extraction filtrate. Detected by ultraviolet detector (UV): the content of anthocyanin in the extract is 0.037%, the calculated amount of pure anthocyanin is: 1.96kg; the extraction recovery rate of anthocyanin is 95.6%.

[0050] 2. Adsorption and elution of medium and low pressure macroporous resin adsorption column:

[0051] The obtained 4900kg elderberry fruit leaching, filtration clear l...

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Abstract

The invention relates to the technical field of extraction of effective parts of plants, in particular to an extraction and separation method of flavone and cyanidin from elderberry fruits. The invention aims to overcome the problems of complicated raw material treatment, low recovery and content of target constituents of products, and poor product color in the prior art. The provided technical proposal is as follows: the extraction and separation method of the flavone and cyanidin from the elderberry fruits comprises the following steps: first, extraction: crushing the raw materials, adding to a container for evenly stirring, dipping and filtering to obtain clear leach solution of the elderberry fruits for use; second, performing adsorption and elution by a macroporous resin adsorption column to obtain a condensed extract; and third, drying the extract to obtain a finished product. Compared with the prior art, the method has the advantages of 1. simple raw material treatment, 2. high recovery and content of target constituents of the product, 3. good color (mauve), and 4. simple process.

Description

Technical field: [0001] The invention relates to the technical field of plant effective parts extraction, in particular to a method for extracting and separating flavonoids and anthocyanins from elderberry fruits. Background technique: [0002] Elderberry, a deciduous shrub to a small tree, is a genus of honeysuckle family, the elderberry fruit is a spherical berry-like drupe. Elderberry contains flavonoids (apigenin, kaempferol, quercetin, luteolin), flavonoid glycosides, anthocyanins and anthocyanins. These natural compounds have the following effects: [0003] 1. It is a strong antioxidant, which can effectively remove oxygen free radicals in the body. It can inhibit the full-stage overflow of oily peroxide, which is more than ten times more effective than vitamin E in preventing oxidation. [0004] 2. Helps prevent a variety of free radical-related diseases, including cancer, heart disease, and premature aging. [0005] 3. Improve blood circulation, enhance the elast...

Claims

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Application Information

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IPC IPC(8): C07D311/40C07D311/62A61K36/35
Inventor 郭为青杨园
Owner SHAANXI MINGRUI NATURAL PRODS
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