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Health products with hypolipemic function, preparation method and usage thereof

A health care product and blood lipid-lowering technology, which can be applied to medical preparations containing active ingredients, pharmaceutical formulations, organic active ingredients, etc., can solve problems such as damage to liver function, hinder long-term use of drugs, kidney damage

Active Publication Date: 2011-10-26
WUXI JIANTE PHARM CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, lipid-lowering drugs include statins, fibrates, niacin, and bile acid chelating agents. Long-term use of these drugs will bring certain adverse reactions, such as increasing the probability of myopathy and rhabdomyolysis, destroying liver function, and causing mild symptoms. Degree of kidney damage, etc., hinder the long-term use of these drugs

Method used

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  • Health products with hypolipemic function, preparation method and usage thereof
  • Health products with hypolipemic function, preparation method and usage thereof
  • Health products with hypolipemic function, preparation method and usage thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0136] Embodiment 1: the preparation of health product of the present invention

[0137] The preparation steps are as follows:

[0138] (1) Preparation of red yeast rice powder

[0139] Soak the rice for 20 hours, dry it, add 8% peptone, 3% agar, 5% glucose, 0.5% silkworm chrysalis amino acid product sold under the silkworm chrysalis amino acid trade name by Huzhou Xintiansi Biotechnology Co., Ltd. by weight of rice, 0.3% Magnesium sulfate and 0.3% potassium dihydrogen phosphate were mixed evenly, and sterilized at a temperature of 115° C. for 90 minutes. After it was cooled, 15% by weight of rice was inserted into the common microbiology center of China Microbiological Culture Collection Management Committee under the trade name Monascus The Monascus strains sold by purpureus are placed in an incubator, and after 10 days at a temperature of 42°C, the cultivation is stopped, and the culture materials are taken out, and the vacuum is carried out by Jiangyin Huajing Pharmaceut...

Embodiment 2

[0160] Embodiment 2: the preparation of health product capsule of the present invention

[0161] Weigh respectively 100 parts by weight, 45 parts by weight, 60 parts by weight, 45 parts by weight and 50 parts by weight of the red yeast rice powder, hawthorn extract, ginkgo leaf extract, cassia seed extract and salvia miltiorrhiza extract prepared in Example 1 , and then mixed to measure the total flavonoid content of 62.5mg / g and the lovastatin content of 3.68mg / g, then add 35 parts by weight of cornstarch to the obtained mixture, then mix evenly, pack into a medicinal rubber shell, and obtain The capsules.

Embodiment 3

[0162] Embodiment 3: the preparation of tablet

[0163] Weigh respectively 100 parts by weight, 65 parts by weight, 50 parts by weight, 25 parts by weight and 60 parts by weight of the red yeast rice powder, hawthorn extract, ginkgo leaf extract, cassia seed extract and salvia miltiorrhiza extract prepared in Example 1 , and then mixed to measure the total flavonoid content of 58.5mg / g and lovastatin content of 3.70mg / g, then add 28 parts by weight of dextrin to the obtained mixture and mix evenly, granulate in one step, add 5 parts by weight of stearin Magnesium acid, then carry out tabletting to obtain described tablet.

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Abstract

The invention relates to health products with hypolipemic function and also relates to a preparation method for the health products and the usage thereof. The health products comprise active constituents of hongqu powder, hawthorn extract, ginkgo biloba leaf extract, obtuseleaf senna seed extract and radix salviae miltiorrhizae extract. The active constituents have very obvious synergistic effect, thus playing a positive role in hypolipemic in many aspects such as reducing endogenous lipid synthesis, promoting the transfer and excretion of lipid, regulating lipid metabolism and the like, having obvious hypolipemic effect; safety toxicity test proves that the active constituents are safe, innoxious and harmless.

Description

【Technical field】 [0001] The invention relates to the technical field of health products. More specifically, the present invention relates to a health care product with the function of lowering blood fat, and also relates to a preparation method of the health care product and their use. 【Background technique】 [0002] In humans, dyslipidemia is a major contributor to atherosclerosis and coronary heart disease. Therefore, lowering blood lipids plays an important role in the primary and secondary prevention of cardiovascular diseases. At present, lipid-lowering drugs include statins, fibrates, niacin, and bile acid chelating agents. Long-term use of these drugs will bring certain adverse reactions, such as increasing the probability of myopathy and rhabdomyolysis, destroying liver function, and causing mild symptoms. Degree of kidney damage, etc., hinder the long-term use of these drugs. Therefore, there is an urgent need to develop a hypolipidemic product that is safe, eff...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/734A61P3/06A61K31/366
Inventor 张连龙
Owner WUXI JIANTE PHARM CO LTD
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