Cyazofamid aqueous emulsion and preparation method thereof

Abstract

Cyazofamid belongs to sulfanilamide imidazole bactericide and has high bioactivity on oomycete fungi such as phytophthora capsici, downy mildew, pseudo downy mildew and pythium and brassica plasmodiophora brassicae of plasmodiophoromycetes. A preparation method for cyazofamid aqueous emulsion has a formulation comprising 1 to 30 percent of the cyazofamid, 2 to 15 percent of emulsifying agent, 0.2 to 5 percent of co-emulsifying agent, 10 to 20 percent of solvent, 10 to 20 percent of latent solvent, 0.1 to 5 percent of anti-freezing agent, 2 to 10 percent of stabilizing agent, 0.1 to 2 percent of defoaming agent, 0.1 to 5 percent of thickening agent, 0.1 to 4 percent of pH value conditioner and the balance of deionized water, and comprises the following steps: adding the latent solvent into the deionized water according to a ratio; dispersing the latent solvent in a high-shear preparation kettle and stirring the solution evenly; adding cyazofamid raw powder and solvent as well as latent solvent mother solution into the solution; shearing the mixed solution at high speed; and finally adding the thickening agent into the mixed and stirring the resulting solution evenly to obtain the cyazofamid aqueous emulsion. The cyazofamid aqueous emulsion is a new environment-friendly water-based dosage form of agricultural bactericide, uses water as a dispersive medium to replace an expensive organic solvent, reduces environment and dust pollution, and is a new dosage form with development prospect.

Description

technical field [0001] The invention relates to a bactericide pesticide cyazofamid aqueous emulsion and a preparation method thereof. technical background [0002] Cyazofamizol belongs to the sulfimidazole fungicides. It has high biological activity against oomycete fungi such as Phytophthora, Peronospora, Pseudomonas, Pythium and Phytophthora brassicae. The mechanism of action is to block mitochondrial cytochrome bc in oomycetes 1 The electron transfer of the complex interferes with the supply of energy, and its binding site is the Q of the enzyme 1 Center, no cross-resistance with other fungicides. Its high selective activity against pathogenic bacteria may be due to the difference in the sensitivity of the target enzyme to the drug. Field application has a very high control effect on late blight and downy mildew, and the dosage is 2-38 times lower than other fungicides. For example, treating potato late blight with a concentration of 50-100mg / L has an outstanding cont...

AI Technical Summary

Problems solved by technology

[0009] In terms of preparations, there are only 10% Cyazofamida Suspension Concentrate and 40% Cyazofamid Granules in China, and there are no patent reports on other Cyazofim single preparations. Therefore, the purpose of the present invention is to be environmentally friendly, efficient, and reduce production costs. Based on the principle of inventing a water emulsion of Cyazofamid and its preparation method