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Bezoar chest functioning preparation and preparation method thereof

A technology of Angong Niuhuang pills and preparations, which is applied in the fields of anti-inflammatory agents, pill delivery, and pharmaceutical formulations, and can solve the problems that the original medicinal materials cannot be fully utilized, the crushed fine powder of medicinal materials has a large particle size, and the bioavailability of medicinal powders is low. Improvement of dissolution rate and bioavailability, high production cost, effect of improving bioavailability

Inactive Publication Date: 2009-11-18
BEIJING HERUN INNOVATION PHARMA TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its curative effect is remarkable, and it is welcomed by the majority of patients, but it is found in practical application that it still has certain defects: the crushed fine powder of medicinal materials in the prescription is too large, and the effect of each component in the medicinal materials cannot be fully exerted.
[0003] Coarse powders have low bioavailability, and the original medicinal materials cannot be fully utilized. Due to the large market demand, the resources of traditional Chinese medicinal materials are seriously wasted.

Method used

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  • Bezoar chest functioning preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Bezoar 20g Concentrated Buffalo Horn Powder 40g Musk 5g Pearl 10g

[0047] Cinnabar 20g Realgar 20g Coptis 20g Scutellaria baicalensis 20g

[0048] Gardenia 20g Turmeric 20g Borneol 5g

[0049] Take the cinnabar and realgar from the above eleven flavors and fly them into fine powder; Coptis chinensis, baicalin, gardenia and tulip are crushed into coarse powder, mixed with bezoar, buffalo horn concentrated powder, musk and borneol, and placed in a vibrating ultrafine pulverizer Pulverize for 30 minutes to obtain an ultrafine pharmaceutical composition, mix evenly with cinnabar and realgar ultrafine powder, add 1.1 times of refined honey, and prepare Angong Niuhuang small honeyed pills or big honeyed pills.

Embodiment 2

[0051] Bezoar 20g Concentrated Buffalo Horn Powder 40g Musk 5g Pearl 10g

[0052] Cinnabar 20g Realgar 20g Coptis 20g Scutellaria baicalensis 20g

[0053] Gardenia 20g Turmeric 20g Borneol 5g

[0054] Take the cinnabar and realgar from the above eleven flavors and fly them into fine powder; Coptis chinensis, baicalin, gardenia and tulip are crushed into coarse powder, mixed with bezoar, buffalo horn concentrated powder, musk and borneol, and placed in a vibrating ultrafine pulverizer Pulverize for 80 minutes to obtain an ultrafine pharmaceutical composition, mix evenly with cinnabar and realgar ultrafine powder, add 0.5 times of refined honey and appropriate amount of water, and obtain Angong Niuhuang water honeyed pills.

Embodiment 3

[0056] Bezoar 20g Concentrated Buffalo Horn Powder 40g Musk 5g Pearl 10g

[0057] Cinnabar 20g Realgar 20g Coptis 20g Scutellaria baicalensis 20g

[0058] Gardenia 20g Turmeric 20g Borneol 5g

[0059] For the above eleven flavors, take cinnabar and realgar and fly them into fine powder; Coptis chinensis, Scutellaria baicalensis, gardenia and tulip are crushed into coarse powder, mixed with bezoar, buffalo horn concentrated powder, musk and borneol, add chitosan 10g, egg Phospholipid 20g, micropowder silica gel 20g and low-substituted hydroxypropyl cellulose 20g were pulverized for 40 minutes by a vibrating ultrafine pulverizer to obtain an ultrafine pharmaceutical composition, which was uniformly mixed with cinnabar and realgar fine powder, and 1.4 times of refining agent was added. honey to make small honeyed pills or big honeyed pills of Angong Niuhuang.

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Abstract

The invention discloses a traditional Chinese medicine preparation, in particular a bezoar chest functioning preparation prepared by adopting an ultrafine grinding technology, and a preparation method thereof. The prescription of the preparation originates from the prior bezoar chest functioning pill, and raw materials are prepared into needed preparation by the conventional technology after being ground by the ultrafine grinding technology. Compared with the prior art, the obtained product maintains active ingredients to the maximum, keeps the compound grinding homogenization, fully embodies the traditional Chinese medicine features, enhances the use ratio of medicinal materials, saves medicine resources and reduces production cost. The invention also discloses a preparation technology of the bezoar chest functioning preparation.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to an Angong Niuhuang preparation prepared by using the prescription of the traditional Chinese medicine "Angong Niuhuang Pills" as a raw material and adopting ultrafine pulverization technology and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Angong Niuhuang Pills are now recorded on page 451 of the 2005 edition of the "Chinese Pharmacopoeia". 100 parts by weight of realgar, 100 parts by weight of berberine, 100 parts by weight of Scutellaria baicalensis, 100 parts by weight of gardenia, 100 parts by weight of turmeric, 25 parts by weight of borneol, with functions of clearing away heat and detoxification, calming convulsions and resuscitation, used for febrile disease, evil entering the pericardium, high fever Convulsions, stupor and delirium; stroke coma and encephalitis, meningitis, toxic encepha...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K36/896A61K9/20A61K9/48A61K47/32A61K47/34A61K47/36A61K47/38A61K47/40A61P29/00A61P9/00A61P7/00A61P25/00A61K31/045A61K33/28A61K33/36A61K35/32A61K35/413A61K35/55A61K35/56A61K47/10A61K47/24
Inventor 武建卓朴美善
Owner BEIJING HERUN INNOVATION PHARMA TECH DEV
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