Brominated butyl rubber plug for sterile powder for injection
A technology of brominated butyl rubber stoppers and brominated butyl rubber, which is applied to the types of packaging items, special packaging items, medical containers, etc., can solve problems such as affecting sealing performance, strict cleaning requirements, and floating chemical indicators, and achieve low Good breathability/vapority, good biological inertness, and small compression deformation
A technology of brominated butyl rubber stoppers and brominated butyl rubber, which is applied to the types of packaging items, special packaging items, medical containers, etc., can solve problems such as affecting sealing performance, strict cleaning requirements, and floating chemical indicators, and achieve low Good breathability/vapority, good biological inertness, and small compression deformation
CN101759937AActive Publication Date: 2010-06-30SHANDONG PHARMA GLASS
Examples
Experimental program
Comparison scheme
Effect test
Embodiment
[0040] 1. Ingredients: According to the ingredients shown in the table below
[0041] Unit(Kg)
[0042] composition
English name
Example 1
Example 2
Example 3
bromobutyl rubber
BIIR
49
49.5
50
Calcined kaolin
43
42.5
42
Stearine Acid
0.4
0.45
0.5
3
2.5
2
Ziuc oxide
2
2.5
3
Phenolic Resin
Phenolic Resine
0.8
0.75
0.7
Titanium dioxide
1
1.5
2
0.2
0.15
0.1
[0043] composition
English name
Example 1
Example 2
Example 3
magnesium oxide
Magnesium xoide
0.2
0.25
0.3
[0044] 2. Preparation process: the ingredients are selected from any one of the formulas in Examples 1-3, and prepared b...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention relates to a brominated butyl rubber plug for sterile powder for injection, which belongs to the technical field of medical bottle plugs and is characterized in that the brominated butyl rubber plug for sterile powder for injection comprises following ingredients in parts by weight: 49 to 50 parts of brominated butyl rubber, 42 to 43 parts of calcined china clay, 0.4 to 0.5 parts ofstearic acid, 2 to 3 parts of Tissuemat E, 2 to 3 parts of zinc oxide, 0.7 to 0.8 parts of phenolic resin, 1 to 2 parts of titanium dioxide, 0.1 to 0.2 parts of soot carbon and 0.2 to 0.3 parts of magnesium oxide. The brominated butyl rubber plug of the invention can be vulcanized by using few cleaning vulcanized agents, has low quantity of auxiliary agents and impurities, and has the advantages of high air / vapor penetration resistance, chemical agent and solvent resistance, ozone resistance, weathering resistance, thermal stability, low compression deformation and good bioinert. The brominated butyl rubber plug of the invention can be widely used for subpackage of antibiotic powder-injection medicine.
Description
technical field [0001] The invention belongs to the technical field of medicinal bottle stoppers, in particular to a bromobutyl rubber stopper for sterile powder for injection. Background technique [0002] Drugs are a special commodity, and their efficacy and quality are directly related to personal health and safety. The materials and structural forms of drug packaging, especially the packaging materials that directly contact drugs, play a decisive role in ensuring the stability of drugs. Unsuitable packaging materials can cause exudation, adsorption, and even chemical reactions of active pharmaceutical ingredients, leading to drug failure and sometimes serious toxic side effects. Therefore, whether the selection of pharmaceutical packaging materials is appropriate is an important indicator for evaluating the quality of pharmaceuticals. [0003] Rubber stoppers are an important part of bottle sealing materials in pharmaceutical packaging, mainly including natural rubber a...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
30 Jun 2010
Publication
CN101759937A
- IPC
- C08L23/28; C08L61/06; C08K13/02; C08K5/09; C08K3/22; C08K3/34; A61J1/00
- Inventors
- 扈永刚; 张军