Polyfluoric terphenyl liquid crystal compound and synthesis method and use thereof
A technology of polyfluoroterphenyls and liquid crystal compounds, which is applied in the field of compounds, can solve problems such as low driving voltage refractive index dielectric anisotropy, and achieve high optical dielectric anisotropy, high electronegativity, lower melting point and The effect of viscosity
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[0018] (1) Preparation of intermediate 4-alkyl fluorine-containing iodobenzene
[0019]
[0020] (2) Preparation of intermediate fluorophenylboronic acid
[0021]
[0022] (3) Preparation of intermediate 4-alkyl fluorinated biphenylboronic acid
[0023]
[0024] (4) Synthesis of the target product polyfluoroterphenyl liquid crystal
[0025]
specific Embodiment
[0026] According to the above synthetic route, the liquid crystal compound——4-(4'-(4"-propyl-2",6"-difluorophenyl)-2',6'-difluorophenyl)-2,6 -The concrete processing steps of difluorobenzene trifluoromethoxy ether are as follows:
[0027] A. Synthesis of 3,5-difluoropropylbenzene
[0028] A1. Add 200g of magnesium chips and 300ml of tetrahydrofuran into a 1-liter three-neck flask, heat and stir until reflux. Stirring was stopped, and a small amount of 3,5-difluorobromobenzene was added dropwise. After the reaction was initiated, 135 g of 3,5-difluorobromobenzene was added dropwise while the reflux was maintained, stirred for 1 hour, and cooled to 30°C for use.
[0029] A2. Add 300ml of tetrahydrofuran, 172g of bromopropane, 3.5g of cuprous chloride, and 2.1g of lithium chloride into a 1-liter three-necked flask, drop into the reagent prepared in step A1 under stirring, stir and reflux for 5 hours, and cool down to 30 Hydrochloric acid hydrolysis at ℃, liquid separation, extr...
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