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Nano silver high-efficiency antibacterial composition used for gynecologic inflammation and preparation method thereof

An antibacterial composition and technology for gynecological inflammation, applied in the direction of antibacterial drugs, drug combinations, medical preparations containing active ingredients, etc., can solve the problems of drug loss, not promoting promotion, inconvenient use of sprays, etc., to avoid external Factors, reducing the burden of treatment costs, and the effect of being convenient for daily use

Inactive Publication Date: 2010-07-14
王明霞 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] 4. The vaginal opening is close to the urethral opening and anus, and is polluted by urine and feces, which is easy to breed germs
[0010] 1. Not paying attention to hygiene during menstruation: using unclean sanitary pads, having sex during menstruation, etc.
[0011] 2. Lax disinfection of uterine cavity surgery
Oral tablets are less absorbed, easily irritate the digestive tract, and need to be taken for a long time; lotions occupy a large market, but because their packaging is generally large and not easy to carry, it has great limitations when traveling on business, and The quality is uneven, the drug ingredients are complicated, and the curative effect is not exact; the spray is inconvenient to use, and the packaging cost is high, so it is not recommended to be promoted; Disadvantages; suppositories are easy to cause drug loss, and the hygiene is poor; when using effervescent tablets alone, due to their violent reaction with water, it is inconvenient to insert, and the drug is not easy to release when the peripheral environment is dry

Method used

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  • Nano silver high-efficiency antibacterial composition used for gynecologic inflammation and preparation method thereof
  • Nano silver high-efficiency antibacterial composition used for gynecologic inflammation and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: the nano-silver high-efficiency antibacterial composition for the treatment of gynecological inflammation, the preparation process is as follows:

[0034] 1. Tablet preparation

[0035] 1.1 Part of effervescent tablet:

[0036] prescription:

[0037] Nano silver 1g

[0038] Lactose 50g

[0039] Citric acid 100g

[0040] Sodium bicarbonate 100g

[0041] Low-substituted hydroxypropyl cellulose 20g

[0042] Magnesium Stearate 2g

[0043] Anhydrous ethanol amount

[0044] Makes 1000 pieces

[0045] Preparation: a) Processing of raw and auxiliary materials: Dry and dehydrate the required raw and auxiliary materials respectively, pass through 100 sieves, and weigh according to the prescription amount for later use. b) Preparation of soft material: Take nano-silver, lactose, citric acid, sodium bicarbonate and low-substituted hydroxypropyl cellulose, mix them uniformly in equal amounts, and prepare soft material with an appropriate amount of absolute eth...

Embodiment 2

[0060] Embodiment 2: the nano-silver high-efficiency antibacterial composition for the treatment of gynecological inflammation, the preparation process is as follows:

[0061] 1. Tablet preparation

[0062] 1.1 Part of effervescent tablet:

[0063] prescription:

[0064] Nano silver 1g

[0065] Mannitol 50g

[0066] Citric acid 80g

[0067] Anhydrous sodium carbonate 100g

[0068] Low-substituted hydroxypropyl cellulose 20g

[0069] Micronized silica gel 2g

[0070] Anhydrous ethanol amount

[0071] Makes 1000 pieces

[0072] Preparation: a) Processing of raw and auxiliary materials: Dry and dehydrate the required raw and auxiliary materials respectively, pass through 100 sieves, and weigh according to the prescription amount for later use. b) Preparation of soft material: Take nano-silver, mannitol, citric acid, anhydrous sodium carbonate and low-substituted hydroxypropyl cellulose, mix them uniformly in equal amounts, and prepare soft material with an appropriate am...

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PUM

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Abstract

The invention discloses a nano silver high-efficiency antibacterial composition used for gynecologic inflammation and a preparation method thereof. The acting component in the formation of the nano silver high-efficiency antibacterial composition is nano silver, and the composition comprises two parts which are respectively a nano silver vaginal effervescent tablet and a slow-release tablet. The invention is suitable for female vaginal application and combined use. When in use, the effervescent tablet is firstly dissolved into water, an affected part is washed, then the slow-release tablet is put into the mixture, the principle of the release of a medicine can be fully utilized, and the sufficient and uniform medicine concentration is ensured, thereby killing pathogenic bacteria quickly and thoroughly and achieving the aim of cure. The combination has convenient use, is also convenient to carry, is easily accepted by a patient and is suitable for clinical popularization and use. The invention also discloses the preparation method. The invention has stable quality of a product, simple preparation process, controllable quality and lower cost, can adapt to industrialized large-scale production, ensures the quality of the product and can also lower the application burden of illness greatly. The composition prepared by the invention is mainly applied to vaginitis, urethritis, pelvic inflammation, cervicitis and the like in the gynecologic inflammation, and the cure rate can reach 90.3 percent.

Description

field of invention [0001] The invention relates to a nano-silver high-efficiency antibacterial composition for gynecological inflammation and a preparation method thereof, belonging to the technical research field of medical devices. technical background [0002] According to authoritative statistics, more than 90% of adult women will suffer from gynecological inflammation once or twice in their lives. Symptoms such as vulvar itching, abnormal leucorrhea, lower abdominal pain, vaginal bleeding, frequent urination, bleeding after intercourse, and irregular menstruation are gynecological inflammation. Omen, gynecological inflammation seriously affects the quality of life of women. Common clinical gynecological inflammations mainly include: vulvitis, vaginitis, cervicitis, Bartholinitis, pelvic inflammatory disease, etc., vulvar itching, burning pain, vaginal congestion, leucorrhea bean dregs, excessive leucorrhea, painful sexual intercourse, frequent urination Symptoms such a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/38A61K9/22A61K9/46A61P15/00A61P15/02A61P31/04
Inventor 王明霞孟桂荣
Owner 王明霞
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