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Atomizing preparation containing plant extract and preparation method thereof

A technology of plant extracts and preparations, which is applied in the field of atomized preparations and its preparation, can solve problems such as difficult absorption, low bioavailability, and poor curative effect, and achieve the goals of high-quality drugs, safe clinical application, and reduced microbial pollution and waste Effect

Active Publication Date: 2012-09-19
上海安焯科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, tea polyphenols are generally used as food additives in China. Oral tea polyphenols are difficult to absorb and have low bioavailability, resulting in poor curative effect.

Method used

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  • Atomizing preparation containing plant extract and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] An atomized preparation containing plant extracts, which consists of 0.01 parts by weight of tea polyphenols, 0.01 parts by weight of vitamin E, 0.001 parts by weight of mint essence and 80 parts by weight of propylene glycol.

[0022] The preparation method of the above-mentioned atomized preparation is as follows: Weigh 5 kg of green tea leaves and coarsely pulverize them with a pulverizer. Reflux extraction with 70vol% ethanol twice, add 7-9 times the volume of ethanol for the first time, 2 hours, 6-8 volumes for the second time, 1 hour, combine the extracts, filter, and recycle the ethanol by vacuum distillation of the filtrate to obtain the first Extraction solution: After the first extraction solution is filtered or centrifuged to remove insoluble matter, the second extraction solution is obtained after concentrating and removing part of the water, which is used in the next process; the chloroform and the second extraction solution are mixed according to the volume...

Embodiment 2

[0024] An atomized preparation containing plant extracts, comprising 20 parts by weight of tea polyphenols, 2 parts by weight of vitamin E, 0.01 parts by weight of mint essence and 99.9 parts by weight of propylene glycol.

[0025] The preparation method of the above-mentioned atomized preparation is as follows: Weigh 5 kg of green tea leaves and coarsely pulverize them with a pulverizer. Reflux extraction with 70vol% ethanol twice, add 7-9 times the volume of ethanol for the first time, 2 hours, 6-8 volumes for the second time, 1 hour, combine the extracts, filter, and recycle the ethanol by vacuum distillation of the filtrate to obtain the first Extraction solution: After the first extraction solution is filtered or centrifuged to remove insoluble matter, the second extraction solution is obtained after concentrating and removing part of the water, which is used in the next process; the chloroform and the second extraction solution are mixed according to the volume ratio of 3...

Embodiment 3

[0027] An atomized preparation containing plant extracts, comprising 10 parts by weight of tea polyphenols, 1 part by weight of vitamin E, 0.1 parts by weight of mint essence and 88.9 parts by weight of propylene glycol.

[0028] The preparation method of the above-mentioned atomized preparation is as follows: Weigh 5 kg of green tea leaves and coarsely pulverize them with a pulverizer. Reflux extraction with 70vol% ethanol twice, add 7-9 times the volume of ethanol for the first time, 2 hours, 6-8 volumes for the second time, 1 hour, combine the extracts, filter, and recycle the ethanol by vacuum distillation of the filtrate to obtain the first Extraction solution: After the first extraction solution is filtered or centrifuged to remove insoluble matter, the second extraction solution is obtained after concentrating and removing part of the water, which is used in the next process; the chloroform and the second extraction solution are mixed according to the volume ratio of 3:2...

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Abstract

The invention provides an atomizing preparation containing plant extract and a preparation method thereof. The atomizing preparation containing plant extract is characterized by comprising tea polyphenol, vitamin E, essence and diluent. The preparation method comprises the following steps of: grinding the green tea by a grinder, refluxing and extracting with ethanol solution, mixing the extract solution and filtering, decompressing and distilling the filtrate to obtain the extract solution; mixing chloroform and the extract solution, stirring the mixture, standing for demixing the mixture, and taking the upper-layer aqueous solution; clarifying the upper-layer aqueous solution by flat ultrafiltration device to obtain the clear solution; freezing and drying the clear solution to obtain thetea polyphenol powder; and mixing the tea polyphenol, the vitamin E, the essence and the diluent according to the percentage. The invention has the advantages of special design and manufacture for the atomizing inhalation of the patients, no preservatives, disposable single dose, convenient and quick use, no need of dilution and preparation and capability of greatly reducing the microorganism pollution and waste in the use course.

Description

technical field [0001] The invention relates to an atomized preparation containing plant extracts and a preparation method thereof. It is suitable for people who have a smoking habit or work in an environment that damages the lungs. Based on the damage to the lungs, the probability of reducing lung diseases belongs to the technical field of traditional Chinese medicine. Background technique [0002] Tea polyphenols are commonly used medicines and food additives. It has been reported in the literature that tea polyphenols can scavenge active oxygen free radicals, block lipid peroxidation, and increase the activity of enzymes in the human body, thus playing the role of anti-mutation and anti-cancer. Tea polyphenols can also induce the increase in the activity of metabolic enzymes in the human body, promote the detoxification of carcinogens, and can inhibit and block the endogenous nitrosation reaction of the human body to prevent cancer and gene mutation. Experiments have sh...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/355A61K9/72A61P11/00A61P39/06
CPCA23V2002/00A61K31/355A61K31/353A61K9/19A61K36/82A61K9/0073A23L1/3002A23L33/105A61P11/00A61P39/06A61K2300/00A23V2250/214A23V2250/712A23V2300/14
Inventor 赵家振陈钰冯小平
Owner 上海安焯科技有限公司