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Medicinal composition for treating skin itch, preparation method and application thereof

A technology of skin pruritus and composition, which is applied in the field of pharmaceutical compositions for treating skin pruritus, can solve the problems of large skin damage and repeated illness, and achieve the effects of definite curative effect, clear material basis, and small toxic and side effects

Inactive Publication Date: 2010-10-13
JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its advantage is that it takes effect quickly and can quickly improve the symptoms of skin itching in patients. However, because it is a chemical drug, it does a lot of damage to the skin, and the condition often recurs

Method used

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  • Medicinal composition for treating skin itch, preparation method and application thereof
  • Medicinal composition for treating skin itch, preparation method and application thereof
  • Medicinal composition for treating skin itch, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The preparation of embodiment 1 pharmaceutical ointment of the present invention

[0032] 1. The preparation method of each crude extract of medicinal taste

[0033] (1) preparation method of paeonol crude extract

[0034] Take the decoction pieces of Moutan cortex, add water 15 times the weight of the decoction pieces, add 5% sodium chloride of the total weight of water, soak for 2 hours, distill with distilled water, collect the distillate of 9 times the weight of the decoction pieces, refrigerate the liquid, filter, Obtain crystals; add the above-mentioned amount of sodium chloride to the filtrate, carry out redistillation, collect redistillate with an amount 3 times the weight of medicinal materials, refrigerate overnight, and filter to obtain crystals. The two cold crystals were combined and dried at 40°C to obtain.

[0035] (2) the preparation method of whitewash crude extract

[0036] Take the coarse powder of white fresh skin, add 10 times the weight of the m...

Embodiment 2

[0057] The preparation of embodiment 2 medicinal powders of the present invention

[0058] Get 150g of peony cortex, 150g of white fresh cortex, 50g of Sophora flavescens, and 600g of licorice, and grind them into fine powders and mix them evenly. Pass through a No. 7 sieve (120 mesh) to get it.

Embodiment 3

[0059] The preparation of embodiment 3 medicinal lotion of the present invention

[0060] Take 20g of peony cortex, 20g of white fresh cortex, 10g of sophora flavescens, and 50g of licorice, add 8 times the amount of water to decoct for 2 hours, add 2g of borneol, 1g of menthol, and 100ml of glycerin to the filtrate, stir evenly, and add water to 1000ml.

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Abstract

The invention provides a medicinal composition for treating skin itch, which is a preparation prepared from the raw material medicaments of cortex moutan radicis, densefruit pittany root-bark, lightyellow sophora root, liquorice root, borneol and menthol crystal. The invention also provides an external medicament which is prepared by taking paeonol extract used as active ingredients in the cortex moutan radicis, dictamnine extract used as active ingredients in the densefruit pittany root-bark, matrine extract used as active ingredients in the lightyellow sophora root, glycyrrhetinic acid extract used as active ingredients in the liquorice root, the borneol and the menthol crystal as active ingredients and adding pharmaceutically-acceptable auxiliary materials or auxiliary components. The invention also provides a preparation method of the medicinal composition. The medicament of the invention can treat the symptom of pruritus caused by accumulating evils of wind heat, moist heat and blood heat in the skin, comprising the pruritus caused by eczema. The medicinal composition of the invention has a refining formula of raw materials, definite material basis, definite curative effect and little toxic or side effect, and particularly has the unique curative effect on pruritus symptom of which the course of disease is lingering and repeated.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating skin pruritus, which belongs to the field of medicines. Background technique [0002] Skin pruritus, also known as "pruritus" or "pruritus" in modern medicine, refers to a skin disease with only itchy skin without significant primary skin lesions. In neurological dysfunction skin diseases. [0003] Regarding the pathogenesis and treatment of skin pruritus, Chinese and Western medicine are different. Western medicine believes that itching, like pain, is caused by non-specific free nerve endings at the epidermis and epidermis-dermis junction. Under normal circumstances, itching and pain are usually along the The same neuron transmits different sensations due to different excitation and inhibition processes in the central nervous system. In fact, itch sensation is centrally regulated by excitatory and inhibitory circuits of neurons located in the jelly of the dorsal pelvic horn, as well ...

Claims

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Application Information

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IPC IPC(8): A61K36/75A61P17/04A61K31/045
Inventor 杨明陈红王达宾朱卫丰王森陈丽华吴德智管咏梅高亚男
Owner JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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