Composition with disintoxicating and liver-protecting effects and application thereof in food and health-care food
A technology for anti-alcoholic and liver-protecting and health food, which is applied in the application field of composition, food and health food with anti-alcoholic and liver-protecting effects, and can solve problems such as insignificant anti-alcoholic effect, unsuitable eating habits, and large body side effects , to prevent and improve excessive drinking, reduce ethanol concentration and active oxygen concentration, and reduce liver damage
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Embodiment 1
[0025] The preparation of embodiment 1 composition chewable tablet of the present invention
[0026] 1. Formula
[0027] Curcumin 29.02g
[0028] Zinc Lactate 7.42g
[0029] Glutamine 480g
[0030] Alanine 480g
[0031] Xylooligosaccharides 375g
[0032] Citric acid 8.37 grams
[0033] Menthol 1.48g
[0034] Peppermint oil 0.20ml
[0035] 2. Granulation and tableting
[0036] Mix curcumin, glutamine, and alanine as a base material, and dissolve xylooligosaccharides, zinc lactate, and citric acid in an equal amount of purified water as a binder, and then granulate in one step. Dissolve menthol and peppermint oil in 75% ethanol, spray into the granules at room temperature, mix well, granulate, pass through a 20-mesh sieve, mix well, add appropriate amount of microcrystalline cellulose and magnesium stearate, mix well, and press into 1000 tablets , each weighing 1.35 grams, that is.
Embodiment 2
[0037] The preparation of embodiment 2 composition granules of the present invention
[0038] 1. Formula
[0039] Curcumin 20.15g
[0040] Zinc Lactate 5.50g
[0041]Glutamine 360g
[0042] Alanine 380g
[0043] Xylooligosaccharides 280g
[0044] 6.05 grams of citric acid
[0045] Menthol 1.10g
[0046] Peppermint oil 0.15ml
[0047] 2. Granulation
[0048] Mix curcumin, glutamine, alanine, as base material, xylooligosaccharide, zinc lactate, lemon
[0049] Acid plus an equal amount of purified water dissolved as a binder, one-step granulation. Dissolve menthol and peppermint oil in 75% ethanol
[0050] solution, sprayed into the granules at room temperature, mixed evenly, granulated, passed through a 20-mesh sieve, and made into 1000 grams of granules.
Embodiment 3
[0051] Embodiment 3 The anti-alcoholic effect of the composition of the present invention on alcohol poisoning mice
[0052] 1. Materials and methods
[0053] 1.1 Animals: healthy Kunming mice, half male and half male, weighing 24-28g
[0054] 1.2 Drugs and reagents
[0055] Complex amino acid chewable tablet (chewable tablet made from the composition of the present invention) aqueous solution: take the tablet, grind it finely, and prepare a suspension with a content of 0.25 g / ml and 0.5 g / ml with water.
[0056] 56° Red Star Erguotou Liquor: Beijing Red Star Co., Ltd.
[0057] Adenosine triphosphate: (ATP), Tween 20, iodonitrotetrazolium violet (INT), phenazine methyl sulfate (PMS), coenzyme I (NAD), alcohol dehydrogenase (ADH) standard, all are Sigma company's product.
[0058] 1.3 Experimental method
[0059] 1.3.1 The effect of prophylactic administration of compound amino acid chewable tablets on the time and rate of drunkenness in mice with acute alcoholism
[0060...
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